[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
Functional imaging of the lungs with gas agents
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe …
PJ Niedbalski, CS Hall, M Castro… - Magnetic resonance …, 2021 - Wiley Online Library
Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …
terminal airway morphology rapidly and safely, providing novel information not possible …
Hyperpolarized 3He and 129Xe MR Imaging in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease
Purpose To quantitatively compare hyperpolarized helium 3 (3He) and xenon 129 (129Xe)
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
[HTML][HTML] Asthma control, airway mucus, and 129Xe MRI ventilation after a single benralizumab dose
Background Patients with eosinophilic asthma often report poor symptomatic control and
quality of life. Anti-IL-5 therapy, including anti-IL-5Rα (benralizumab), rapidly depletes …
quality of life. Anti-IL-5 therapy, including anti-IL-5Rα (benralizumab), rapidly depletes …
Hyperpolarized 3He and 129Xe MRI: Differences in asthma before bronchodilation
S Svenningsen, M Kirby, D Starr… - Journal of magnetic …, 2013 - Wiley Online Library
Purpose To compare hyperpolarized helium‐3 (3He) and xenon‐129 (129Xe) MRI in
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
Effects of dupilumab on mucus plugging and ventilation defects in patients with moderate-to-severe asthma: a randomized, double-blind, placebo-controlled trial
S Svenningsen, M Kjarsgaard, E Haider… - American Journal of …, 2023 - atsjournals.org
Methods We completed a single-center, randomized, double-blind, placebo-controlled trial
(ClinicalTrials. gov identifier NCT 03884842) in 25 adults with uncontrolled moderate to …
(ClinicalTrials. gov identifier NCT 03884842) in 25 adults with uncontrolled moderate to …
129Xe MRI ventilation defects in ever-hospitalised and never-hospitalised people with post-acute COVID-19 syndrome
HK Kooner, MJ McIntosh… - BMJ open …, 2022 - bmjopenrespres.bmj.com
Background Patients often report persistent symptoms beyond the acute infectious phase of
COVID-19. Hyperpolarised 129Xe MRI provides a way to directly measure airway functional …
COVID-19. Hyperpolarised 129Xe MRI provides a way to directly measure airway functional …
CT and Functional MRI to Evaluate AirwayáMucus in Severe Asthma
Background Intraluminal contributor (s) to airflow obstruction in severe asthma are patient-
specific and must be evaluated to personalize treatment. The occurrence and functional …
specific and must be evaluated to personalize treatment. The occurrence and functional …
Regional Ventilation Changes in Severe Asthma after Bronchial Thermoplasty with 3He MR Imaging and CT
RP Thomen, A Sheshadri, JD Quirk, J Kozlowski… - Radiology, 2015 - pubs.rsna.org
Purpose To quantify regional lung ventilation in healthy volunteers and patients with severe
asthma (both before and after thermoplasty) by using a combination of helium 3 (3He) …
asthma (both before and after thermoplasty) by using a combination of helium 3 (3He) …