The potential role of immunotherapy to treat colorectal cancer

M Amin, AC Lockhart - Expert opinion on investigational drugs, 2015 - Taylor & Francis
Introduction: Colorectal cancer (CRC) is the fourth most common cancer and the second
leading cause of cancer-related death worldwide. Surgery, chemotherapy, radiation therapy …

Nanoengineered strategies to optimize dendritic cells for gastrointestinal tumor immunotherapy: from biology to translational medicine

A Bhargava, N Bunkar, NK Khare, D Mishra… - …, 2014 - Future Medicine
Nanomedicine may play an important role in improving the clinical efficacy of dendritic cell-
based immunotherapy against GI tract malignancies. Dendritic cell-based vaccines have …

The Hedgehog inhibitor cyclopamine impairs the benefits of immunotherapy with activated T and NK lymphocytes derived from patients with advanced cancer

H Onishi, T Morisaki, A Kiyota, N Koya… - Cancer Immunology …, 2013 - Springer
Hedgehog (Hh) signaling is activated in various types of cancer and contributes to the
progression, proliferation, and invasiveness of cancer cells. Many Hh inhibitors are …

Efficacy of intranodal neoantigen peptide-pulsed dendritic cell vaccine monotherapy in patients with advanced solid tumors: A retrospective analysis

T Morisaki, T Morisaki, M Kubo, H Onishi… - Anticancer …, 2021 - ar.iiarjournals.org
Abstract Background/Aim: Neoantigens are tumor-specific antigens that emerge due to gene
mutations in tumor cells, and are highly antigenic epitopes that escape central immune …

Engineered dendritic cells for gastrointestinal tumor immunotherapy: opportunities in translational research

A Bhargava, D Mishra, S Banerjee… - Journal of Drug …, 2013 - Taylor & Francis
Gastrointestinal (GI) malignancies are one of the most frequently occurring tumors found
worldwide. Surgery remains the primary treatment for most solid tumors and adjuvant …

Microencapsulation of tumor lysates and live cell engineering with MIP-3α as an effective vaccine

F Huang, F Huang, B Chen, Q Liu, H Wang, S Zhou… - Biomaterials, 2015 - Elsevier
The combination of several potential strategies so as to develop new tumor vaccines is an
attractive field of translational medicine. Pulsing tumor lysates with dendritic cells (DCs), in …

Random migration contributes to cytotoxicity of activated CD8+ T-lymphocytes but not NK cells

H Onishi, A Kiyota, N Koya, H Tanaka… - Anticancer …, 2014 - ar.iiarjournals.org
Activated lymphocytes have the ability to undergo non-directional cell movement known as
random migration, although the biological role for this remains unclear. Herein, we …

保肛术与Miles 术治疗直肠癌的疗效对比

赵淑霞 - 中国社区医师: 医学专业, 2013 - cqvip.com
目的: 探讨临床治疗直肠癌的有效术式. 方法: 收治直肠癌患者73 例, 根据术式将上述患者分为
研究组41 例与对照组32 例; 研究组接受保肛术治疗, 对照组接受Miles 术治疗 …

Trypanosoma cruzi infection decreases malignant melanoma development and increases survival in C57BL/6 mice

DA Morillo, BE González, AJ Sulbaran Larrarte… - Investigación …, 2014 - ve.scielo.org
La infección por Trypanosoma cruzi disminuye el desarrollo del melanoma maligno e
incrementa la supervivencia en ratones C57BL/ Page 1 La infección por Trypanosoma cruzi …

Prediction and identification of B cell epitopes derived from EWS/FLI-l fusion protein of Ewing's sarcoma

H Liu, L Huang, J Luo, W Chen, Z Zhang, X Liao… - Medical Oncology, 2012 - Springer
To predict B cell epitope of Ewing's sarcoma EWS/FLI-l fusion protein and to analyze its
antigenicity and immunogenicity. Comprehensive algorithms were applied to predict the …