Survival and quality of life of dialysis patients are strictly dependent on the quality of the
haemodialysis (HD) treatment. In this respect, dialysate composition, including water purity …

The optimal approach to managing acid-base balance is less well defined for patients
receiving hemodialysis than for those receiving peritoneal dialysis. Interventional studies in …

Prevalence of acidosis and inflammation and their association with low serum albumin in
chronic kidney disease. Background Low serum albumin is a strong risk factor for mortality …

Background The cytochrome P450 (CYP) oxidative enzyme system, located primarily in the
liver and small intestine, is responsible for metabolism and detoxification of numerous …

Metabolic acidosis is a common complication of chronic kidney disease; it is typically caused
by the accumulation of sulfate, phosphorus, and organic anions. Metabolic acidosis is …

Acid‐base equilibrium is a complex and vital system whose regulation is impaired in chronic
kidney disease (CKD). Metabolic acidosis is a common complication of CKD. It is typically …

Abstract Adjustment of bath [HCO3−] to “normalize” predialysis serum [HCO3−] in patients
receiving intermittent hemodialysis has been advocated to prevent the adverse effects of …

Chronic metabolic acidosis is common in dialysis patients. Bicarbonate administration via
the dialysate helps maintain the acid–base balance in these patients. Serum bicarbonate …

The use of high dialysate bicarbonate for hemodialysis in end-stage renal disease is
associated with increased mortality, but potential physiological mediators are poorly …

The acid-base goal of intermittent hemodialysis is to replenish buffers consumed by
endogenous acid production and expansion acidosis in the period between treatments. The …