Acid‐base assessment of patients receiving conventional hemodialysis (HD) has been
based solely on predialysis serum [total CO 2], and treatment is currently driven by the …

We present a patient receiving hemodialysis with a persistently high serum bicarbonate
concentration to illustrate the evaluation and management issues for patients with both high …

Metabolic acidosis is often observed in advanced chronic kidney disease, with deleterious
consequences on the nutritional status, bone and mineral status, inflammation and mortality …

Acid-base profile in patients on PD. Secular trends in dialysis dose in peritoneal dialysis
(PD) and modes of dialysis delivery [automated PD (APD) versus continuous ambulatory PD …

Background Some nephrologists have advocated an individualized approach to the
prescription of bicarbonate hemodialysis. However, the utility of monthly serum bicarbonate …

Introduction: The optimal dialysate bicarbonate concentration (DBIC) for hemodialysis (HD)
remains controversial. Herein, we analyzed the effect of dialysate bicarbonate levels on …

Most End-Stage Renal Disease (ESRD) patients receiving dialysis therapy are in a state of
constant metabolic acidosis which is associated with high cardiovascular morbidity and …

Buffer transport in peritoneal dialysis. The success of peritoneal dialysis as a robust modality
of renal replacement therapy has invited a quest for ameliorations in its underlying …

Hemodialysis requires the use of high volumes of freshly prepared, clean dialysate to foster
the removal of low molecular weight metabolites (ie, urea) and to correct the electrolyte and …

We describe here acid–base physiology in humans who eat typical modern American diets
(5, 6), and argue that, owing to the nature of those diets and the effects of aging, many …