Impact of direct oral anticoagulant off‐label doses on clinical outcomes of atrial fibrillation patients: a systematic review
J Santos, N António, M Rocha… - British Journal of Clinical …, 2020 - Wiley Online Library
Aims Worldwide observational studies are evidencing discordance between guidelines and
real‐world practice regarding direct oral anticoagulant drug (DOAC) doses. This systematic …
real‐world practice regarding direct oral anticoagulant drug (DOAC) doses. This systematic …
Efficacy and safety of direct oral factor Xa inhibitors compared with warfarin in patients with morbid obesity: a single-centre, retrospective analysis of chart data
M Kushnir, Y Choi, R Eisenberg, D Rao… - The Lancet …, 2019 - thelancet.com
Background Because studies of direct oral anticoagulants in patients with venous
thromboembolism and non-valvular atrial fibrillation have had minimal representation of …
thromboembolism and non-valvular atrial fibrillation have had minimal representation of …
[HTML][HTML] Does one dose really fit all? On the monitoring of direct oral anticoagulants: a review of the literature
T Moner-Banet, L Alberio, PA Bart - Hämostaseologie, 2020 - thieme-connect.com
Background There is an increasing amount of literature on direct oral anticoagulant (DOAC)
laboratory monitoring. The aims of the present review were to evaluate published data on …
laboratory monitoring. The aims of the present review were to evaluate published data on …
Impact of BMI on clinical outcomes of NOAC therapy in daily care-Results of the prospective Dresden NOAC Registry (NCT01588119)
L Tittl, S Endig, S Marten, A Reitter… - International journal of …, 2018 - Elsevier
Direct acting non-Vitamin K antagonist oral anticoagulants (NOAC) are characterized by a
fixed dosing regimen. Despite the potential for relative underdosing due to large distribution …
fixed dosing regimen. Despite the potential for relative underdosing due to large distribution …
[HTML][HTML] Effectiveness and safety of oral anticoagulants among NVAF patients with obesity: insights from the ARISTOPHANES study
S Deitelzweig, A Keshishian, A Kang… - Journal of clinical …, 2020 - mdpi.com
This ARISTOPHANES analysis examined stroke/systemic embolism (SE) and major
bleeding (MB) among a subgroup of nonvalvular atrial fibrillation (NVAF) patients with …
bleeding (MB) among a subgroup of nonvalvular atrial fibrillation (NVAF) patients with …
[HTML][HTML] Construction of warfarin population pharmacokinetics and pharmacodynamics model in Han population based on Bayesian method
X Xia, X Cai, J Chen, S Jiang, J Zhang - Scientific Reports, 2024 - nature.com
The purpose of this paper is to study the genetic polymorphisms of related gene loci
(CYP2C9* 3, VKORC1-1639G> A) based on demographic and clinical factors, and use the …
(CYP2C9* 3, VKORC1-1639G> A) based on demographic and clinical factors, and use the …
A single center retrospective cohort study evaluating use of direct oral anticoagulants (DOACs) in morbidly obese veteran population
T Patil, M Lebrecht - Thrombosis research, 2020 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are preferred over warfarin for the
treatment of venous thromboembolism (VTE) as well as atrial fibrillation (AF). The efficacy …
treatment of venous thromboembolism (VTE) as well as atrial fibrillation (AF). The efficacy …
[HTML][HTML] Rivaroxaban pharmacokinetics in obese subjects: a systematic review
Introduction Venous thromboembolism (VTE) is a leading cause of morbidity and mortality
globally. The direct oral anticoagulants, including rivaroxaban, are relatively novel …
globally. The direct oral anticoagulants, including rivaroxaban, are relatively novel …
Body mass index influence on the clinical outcomes for nonvalvular atrial fibrillation patients admitted to a hospital treated with direct oral anticoagulants: a …
X Li, C Zuo, Q Ji, Y Xue, Z Wang… - Drug design, development …, 2021 - Taylor & Francis
Background Considering that the current fixed dose of direct oral anticoagulants (DOACs)
might have insufficient anticoagulation effect for overweight patients, the aim of this study …
might have insufficient anticoagulation effect for overweight patients, the aim of this study …
[HTML][HTML] Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
Purpose To investigate real-world prescribing trends and clinical outcomes based on body
mass index (BMI) categorization in patients who received rivaroxaban therapy. Methods This …
mass index (BMI) categorization in patients who received rivaroxaban therapy. Methods This …