Long-read sequencing technologies have now reached a level of accuracy and yield that
allows their application to variant detection at a scale of tens to thousands of samples …

Chromosomal rearrangements (CRs) have been known since almost the beginning of
genetics. While an important role for CRs in speciation has been suggested, evidence …

Calling structural variations (SVs) is technically challenging, but using long reads remains
the most accurate way to identify complex genomic alterations. Here we present Sniffles2 …

Since allozymes were first used to assess genetic diversity in the 1960s and 1970s,
biologists have attempted to characterize gene pools and conserve the diversity observed in …

Abstract Long-read Structural Variation (SV) calling remains a challenging but highly
accurate way to identify complex genomic rearrangements. Here, we present Sniffles2 …

Research on the genomic architecture of speciation has increasingly revealed the
importance of structural variants (SVs) that affect the presence, abundance, position, and/or …

The increased capacity of DNA sequencing has significantly advanced our understanding of
the phylogeny of birds and the proximate and ultimate mechanisms molding their genomic …

Yak has been subject to natural selection, human domestication and interspecific
introgression during its evolution. However, genetic variants favored by each of these …

Long-read sequencing has demonstrated great potential for characterizing all types of
structural variations (SVs). However, existing algorithms have insufficient sensitivity and …

Understanding the genetic basis of reproductive isolation is a central issue in the study of
speciation. Structural variants (SVs); that is, structural changes in DNA, including inversions …