[HTML][HTML] Cell death regulation: a new way for natural products to treat osteoporosis

Z Li, D Li, R Chen, S Gao, Z Xu, N Li - Pharmacological Research, 2023 - Elsevier
Osteoporosis is a common metabolic bone disease that results from the imbalance of
homeostasis within the bone. Intra-bone homeostasis is dependent on a precise dynamic …

[HTML][HTML] Oxidative stress: A common pathological state in a high-risk population for osteoporosis

C Zhang, H Li, J Li, J Hu, K Yang, L Tao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Osteoporosis is becoming a major concern in the field of public health. The process of bone
loss is insidious and does not directly induce obvious symptoms. Complications indicate an …

Molecular and cellular mechanisms of osteoporosis

IV Zhivodernikov, TV Kirichenko, YV Markina… - International journal of …, 2023 - mdpi.com
Osteoporosis is a widespread systemic disease characterized by a decrease in bone mass
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …

Anti-inflammatory and antioxidant traditional Chinese Medicine in treatment and prevention of osteoporosis

Q Li, C Tian, X Liu, D Li, H Liu - Frontiers in Pharmacology, 2023 - frontiersin.org
A metabolic bone disorder called osteoporosis is characterized by decreased bone mass
and compromised microarchitecture. This condition can deteriorate bones and raise the risk …

Orcinol glucoside targeted p38 as an agonist to promote osteogenesis and protect glucocorticoid-induced osteoporosis

W Zhao, LP Yao, P Sun, G Cheng, YL Liu, Y Yu, Y Liu… - Phytomedicine, 2023 - Elsevier
Background Glucocorticoids (GC)-induced osteoporosis (GIOP) is the most common cause
of secondary osteoporosis, which leads to an increased risk of fracture in patients. The …

Resveratrol ameliorates high altitude hypoxia-induced osteoporosis by suppressing the ROS/HIF signaling pathway

C Yan, Z Wang, W Liu, L Pu, R Li, C Ai, H Xu, B Zhang… - Molecules, 2022 - mdpi.com
Hypoxia at high-altitude leads to osteoporosis. Resveratrol (RES), as an antioxidant, has
been reported to promote osteoblastogenesis and suppress osteoclastogenesis. However …

The Potential of Natural Compounds Regulating Autophagy in the Treatment of Osteoporosis

Y Zhao, Z Qu, S Zhao, Y Zhang, Y Gong… - Journal of …, 2023 - Taylor & Francis
The maintenance of bone homeostasis is dynamically regulated by osteoblast-mediated
bone formation and osteoclast-mediated bone resorption. Abnormal differentiation of …

[HTML][HTML] Anemoside B4 attenuates RANKL-induced osteoclastogenesis by upregulating Nrf2 and dampens ovariectomy-induced bone loss

Z Cao, X Niu, M Wang, S Yu, M Wang, S Mu… - Biomedicine & …, 2023 - Elsevier
Increased numbers and functional overactivity of osteoclasts are the pathological basis for
bone loss diseases such as osteoporosis, which are characterized by cortical bone thinning …

The pathogenesis of post-stroke osteoporosis and the role oxidative stress plays in its development

JY Li, L Shi, JM Sun - Frontiers in Medicine, 2023 - frontiersin.org
Cardiovascular disease and osteoporotic fractures (OF) are the main diseases affecting the
health of middle-aged and elderly people. With the gradual increase of population aging in …

Prevention and treatment of osteoporosis with natural products: Regulatory mechanism based on cell ferroptosis

Y Yang, Y Jiang, D Qian, Z Wang, L Xiao - Journal of Orthopaedic Surgery …, 2023 - Springer
Context With the development of society, the number of patients with osteoporosis is
increasing. The prevention and control of osteoporosis has become a serious and urgent …