While the field of biocatalysis has bloomed over the past 20–30 years, advances in the
understanding and improvement of carbohydrate-active enzymes, in particular, the sugar …

Linear d‐glucans are natural polysaccharides of simple chemical structure. They are
comprised of d‐glucosyl units linked by a single type of glycosidic bond. Noncovalent …

Sialic acids are part of the outermost component of the glycocalyx of all vertebrates; as such,
they are fundamental markers in physiological and pathological processes. In this study, we …

Carbohydrate-active enzymes (CAZymes) are responsible for the biosynthesis, modification
and degradation of all glycans in Nature. Advances in genomic and metagenomic …

Lysosomal accumulation of the glycosphingolipid globotriaosylceramide Gb3 is linked to the
deficient activity of the α-galactosidase A in the Anderson–Fabry disease and an elevated …

Chemical tools enable precise characterization of many biopolymers, including
glycoconjugates. Metabolic chemical reporters enabled the discovery of glycoRNAs …

Protein post-translational modifications (PTMs), which include covalent addition of functional
groups to proteins and removal of specific amino acid (s) from proteins after synthesis, are …

The glycobiology of bacteria is fundamental to understanding many aspects of their
behaviour and how they interact with their environments, infect hosts, and transition between …

Abstract Coronavirus disease 2019 (COVID-19) is a new global pandemic with high
morbidity and mortality caused by severe acute respiratory syndrome coronavirus 2 (SARS …

Enzyme engineering and discovery are crucial for a future sustainable bioeconomy, and
harvesting new biocatalysts from large libraries through directed evolution or functional …