[HTML][HTML] The balance between antibiotic resistance and fitness/virulence in Pseudomonas aeruginosa: an update on basic knowledge and fundamental research
E Jordana-Lluch, IM Barceló… - Frontiers in …, 2023 - frontiersin.org
The interplay between antibiotic resistance and bacterial fitness/virulence has attracted the
interest of researchers for decades because of its therapeutic implications, since it is …
interest of researchers for decades because of its therapeutic implications, since it is …
Drug interactions of carbonic anhydrase inhibitors and activators
CT Supuran - Expert Opinion on Drug Metabolism & Toxicology, 2024 - Taylor & Francis
ABSTRACT Introduction Carbonic anhydrases (CAs, EC 4.2. 1.1) have been established
drug targets for decades, with their inhibitors and activators possessing relevant …
drug targets for decades, with their inhibitors and activators possessing relevant …
A comprehensive investigation of the anion inhibition profile of a β-carbonic anhydrase from Acinetobacter baumannii for crafting innovative antimicrobial treatments
This study refers to the intricate world of Acinetobacter baumannii, a resilient pathogenic
bacterium notorious for its propensity at antibiotic resistance in nosocomial infections …
bacterium notorious for its propensity at antibiotic resistance in nosocomial infections …
[HTML][HTML] Seasonal meropenem resistance in Acinetobacter baumannii and influence of temperature-driven adaptation
X Liu, P Qin, H Wen, W Wang, J Zhao - BMC microbiology, 2024 - Springer
Background Recognition of seasonal trends in bacterial infection and drug resistance rates
may enhance diagnosis, direct therapeutic strategies, and inform preventive measures …
may enhance diagnosis, direct therapeutic strategies, and inform preventive measures …
[HTML][HTML] Drug Discovery in the Field of β-Lactams: An Academic Perspective
LMC Jacobs, P Consol, Y Chen - Antibiotics, 2024 - mdpi.com
β-Lactams are the most widely prescribed class of antibiotics that inhibit penicillin-binding
proteins (PBPs), particularly transpeptidases that function in peptidoglycan synthesis. A …
proteins (PBPs), particularly transpeptidases that function in peptidoglycan synthesis. A …
Carbonic anhydrases in bacterial pathogens
RE Braga, FZ Najar, CL Murphy… - The …, 2024 - pubmed.ncbi.nlm.nih.gov
Carbonic anhydrases (CAs) catalyze the reversable hydration of carbon dioxide to
bicarbonate placing them into the core of the biochemical carbon cycle. Due to the …
bicarbonate placing them into the core of the biochemical carbon cycle. Due to the …