The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are
now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

While the COVID-19 pandemic seems to be on its decline, the unclear impacts of long-
COVID cases, breakthrough infections in immunocompromised individuals, vaccine …

Background Repurposed drugs with host-directed antiviral and immunomodulatory
properties have shown promise in the treatment of COVID-19, but few trials have studied …

As lactoferrin is a nutritional supplement with proven antiviral and immunomodulatory
abilities, it may be used to improve the clinical course of COVID-19. The clinical efficacy and …

Abstract The Ca2+ activated Cl− channel TMEM16A (anoctamin 1; ANO1) is expressed in
secretory epithelial cells of airways and intestine. Previous studies provided evidence for a …

Background During pandemics, early outpatient treatments reduce the health system
burden. Randomized controlled trials (RCTs) in COVID-19 outpatients have tested …

Simple Summary The human body is composed of hundreds of different normal cell types.
Some of the important and unique features of these normal cell types are inherited by the …

Simple Summary Novel pharmacological approaches are needed to improve treatments of
advanced cancers, despite the considerable benefit of immunotherapy. New drugs are …