Physicochemical modeling and characterization of the adsorption mechanism of seven pharmaceutical molecules onto SARS-CoV-2 virus
O Kouira, S Bayoudh, H Smati, M Bouzid… - Materials Chemistry and …, 2023 - Elsevier
The aim of this work is to facilitate the fight against COVID-19 pandemic using a comparative
study of seven drug molecules, in order to select the most efficient drug molecules. This …
study of seven drug molecules, in order to select the most efficient drug molecules. This …
Dry powder formulation of azithromycin for COVID-19 therapeutics
SHY Chan, K Sheikh, MG Zariwala… - Journal of …, 2023 - Taylor & Francis
Azithromycin is an antibiotic proposed as a treatment for the coronavirus disease 2019
(COVID-19) due to its immunomodulatory activity. The aim of this study is to develop dry …
(COVID-19) due to its immunomodulatory activity. The aim of this study is to develop dry …
Predicting lung exposure of intramuscular niclosamide as an antiviral agent: Power‐law based pharmacokinetic modeling
T Kim, W Jung, S Cho, G Kim, H Yun… - Clinical and …, 2024 - Wiley Online Library
Niclosamide, a potent anthelmintic agent, has emerged as a candidate against COVID‐19 in
recent studies. Its formulation has been investigated extensively to address challenges …
recent studies. Its formulation has been investigated extensively to address challenges …
[HTML][HTML] Antiparasitic drugs against SARS-CoV-2: a comprehensive literature survey
E Calvo-Alvarez, M Dolci, F Perego, L Signorini… - Microorganisms, 2022 - mdpi.com
More than two years have passed since the viral outbreak that led to the novel infectious
respiratory disease COVID-19, caused by the SARS-CoV-2 coronavirus. Since then, the …
respiratory disease COVID-19, caused by the SARS-CoV-2 coronavirus. Since then, the …
[HTML][HTML] In Vitro Evaluation and Mitigation of Niclosamide's Liabilities as a COVID-19 Treatment
JW Wotring, SM McCarty, K Shafiq, CJ Zhang… - Vaccines, 2022 - mdpi.com
Niclosamide, an FDA-approved oral anthelmintic drug, has broad biological activity
including anticancer, antibacterial, and antiviral properties. Niclosamide has also been …
including anticancer, antibacterial, and antiviral properties. Niclosamide has also been …
Regulation of autophagy by SARS-CoV-2 and host proteins
L Koepke - 2023 - oparu.uni-ulm.de
Autophagy is an auto-digestive process targeting cytoplasmic cargo for lysosomal
degradation. It is crucial for maintaining cellular homeostasis, and dysregulation of …
degradation. It is crucial for maintaining cellular homeostasis, and dysregulation of …
[HTML][HTML] COVID-19: An update with future urgent priorities and a case study of repurposing drug design
JS Novais, RB Geraldo, CF Mattos, VGO Evangelho… - 2024 - aber.apacsci.com
SARS-CoV-2 is highly transmissible and pathogenic, with nearly 6.5 million infected people
dying worldwide. A severe acute respiratory syndrome is one of the primary COVID-19 …
dying worldwide. A severe acute respiratory syndrome is one of the primary COVID-19 …
Broad-spectrum RNA prophylactic and therapeutic interventions for SARS-CoV-2
A Gontu - 2024 - etda.libraries.psu.edu
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the cause of
coronavirus disease-2019 (COVID-19) pandemic is undergoing continuous evolution …
coronavirus disease-2019 (COVID-19) pandemic is undergoing continuous evolution …
Remote Clinical trials Operations: Supply Chain Management and Framework Development
I Ait Mbiriq - 2022 - dspace.mit.edu
Remote clinical trials present the new approach of revolutionizing traditional clinical trials in
order to decrease costs, accelerate the processes and improve the experience for …
order to decrease costs, accelerate the processes and improve the experience for …
Leveraging Covalent Modification for Diverse Applications in Antiviral Discovery and Kinase Mechanism Deconvolution
JJ Feng - 2022 - search.proquest.com
Covalent target modification has re-emerged in recent years as a promising modality for
therapeutic development and mechanistic biochemical analysis. Although slightly colored by …
therapeutic development and mechanistic biochemical analysis. Although slightly colored by …