Azines, such as pyridines, quinolines, pyrimidines, and pyridazines, are widespread
components of pharmaceuticals. Their occurrence derives from a suite of physiochemical …

N-heterocycles are important, not only because of their abundance, but above all because of
their chemical, biological and technical significance. They play an important role in …

Transition metals, which are of diversity in their bonding orbitals, have a variety of significant
oxidation states and more complex chemical properties compared to the main group metals …

Herein we disclose a strategy to promote the hydrocarboxylation of unactivated alkenes
using photochemical activation of formate salts. We illustrate that an alternative initiation …

Dearomatization reactions have become fundamental chemical transformations in organic
synthesis since they allow for the generation of three-dimensional complexity from two …

Herein, we report a method for C3-selective C–H tri-and difluoromethylthiolation of
pyridines. The method relies on borane-catalyzed pyridine hydroboration for generation of …

Herein we disclose a new photochemical process to prepare carboxylic acids from formate
salts and alkenes. This redox-neutral hydrocarboxylation proceeds in high yields across …

A Ni-catalyzed enantioselective reductive three-component alkylalkenylation of β, γ-alkenyl
ketones with cis-alkenyl iodides and fluoroalkyl iodides in the presence of Mn is reported. By …

A chiral phosphine oxide-ligated Ni–Al bimetallic catalyst was used to realize an
enantioselective C2–H alkylation of pyridines without the need of a C2-block. A wide range …

Immunogenic cell death (ICD) can activate the anticancer immune response and is highly
attractive to improve cancer treatment efficacy. ICD is closely related to endoplasmic …