Preclinical evaluation of perifosine as a potential promising anti-rhabdomyosarcoma agent

J Shen, Y Hong, Q Zhao, J Zhang - Tumor Biology, 2016 - Springer
Rhabdomyosarcoma (RMS) is a highly malignant and metastatic pediatric cancer that arises
from the skeletal muscle. Recent studies have identified an important role of AKT signaling …

[HTML][HTML] Mecanismos moleculares emergentes y células madre leucémicas en la quimiorresistencia de tumores hematológicos

LA Rey-Caro, P Pinzón… - Revista de la Universidad …, 2020 - scielo.org.co
Las leucemias agudas son trastornos clonales originados a partir de células
hematopoyéticas primitivas multipotenciales que se caracterizan por la proliferación …

ROS/mtROS promotes TNTs formation via PI3K/AKT/mTOR pathway to protect against mitochondrial damages induced by engineering nanomaterialsin human glial …

X Lin, W Wang, X Chang, C Chen, Z Guo, G Yu… - 2023 - researchsquare.com
Background As the demand and application of engineering nanomaterials rise, their
potential toxicity in the central nervous system has drawn increasing concerns. As a novel …

Untersuchungen zur Proliferation und Apoptose an normalen hämatopoetischen Progenitorzellen und an Zellen aus Linien hämatopoetischer Malignome unter dem …

R Dabrowski - 2020 - refubium.fu-berlin.de
Einleitung: Perifosin ist ein Alkylphospholipid und Inhibitor des in vielen Tumoren aktivierten
PI3K/Akt/mTOR Signalweges. Aufgrund seines günstigen Toxizitätsprofils wurde Perifosin in …

Emerging molecular mechanisms and leukemic stem cells in chemoresistance of hematologic tumors

LA Rey-Caro, P Pinzón… - Revista de la Universidad …, 2020 - scielo.org.co
Abstract REY-CARO, Luz-Aida; PINZON, Paula and CRUZ-RODRIGUEZ, Nataly. Emerging
molecular mechanisms and leukemic stem cells in chemoresistance of hematologic tumors …

Novel Akt Pathway Inhibitors: An Integrated Approach Between Theory And Experiment

N Uko - 2019 - ursa.mercer.edu
The AKT kinase signaling pathway regulates growth and survival of cells, and it is linked to
the progression of numerous types of human cancers. Several studies have shown that …

[PDF][PDF] Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy

F Mollinedo, C Vandier - 2016 - researchgate.net
Paul-Alain Jaffrès a, e, Consuelo Gajate b, Ana Maria Bouchet c, e, Hélène Couthon-
Gourvès a, e, Aurélie Chantôme c, e, Marie Potier-Cartereau c, e, Pierre Besson c, e …

[PDF][PDF] Determining the Function of Plasmodium Hemolysin III and Discovery of Novel Antimalarial Drugs

NG Robinett - 2015 - jscholarship.library.jhu.edu
Elimination of the malaria parasite from endemic areas requires a multi-faceted approach,
including development of novel antimalarial drugs and a deeper understanding of parasite …

[引用][C] SATB1 通过PI3K/Akt 信号通路在哌立福新对胃癌失巢凋亡抵抗细胞作用机制中的研究

秦玉萍, 高迎新, 马熙萌, 杜瑶, 王新, 禹莉 - 中国免疫学杂志, 2021