[HTML][HTML] The role of cGAS-STING signaling in pulmonary fibrosis and its therapeutic potential

J Zhang, L Zhang, Y Chen, X Fang, B Li… - Frontiers in …, 2023 - frontiersin.org
Pulmonary fibrosis is a progressive and ultimately fatal lung disease, exhibiting the
excessive production of extracellular matrix and aberrant activation of fibroblast. While …

[HTML][HTML] Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma

JT Low, MC Brown, ZJ Reitman… - The Journal of …, 2024 - Am Soc Clin Investig
Since the discovery that cGAS/STING recognizes endogenous DNA released from dying
cancer cells and induces type I interferon and antitumor T cell responses, efforts to …

[HTML][HTML] At the Crossroads of the cGAS-cGAMP-STING Pathway and the DNA Damage Response: Implications for Cancer Progression and Treatment

TV Korneenko, NB Pestov, IA Nevzorov, AA Daks… - Pharmaceuticals, 2023 - mdpi.com
The evolutionary conserved DNA-sensing cGAS-STING innate immunity pathway represents
one of the most important cytosolic DNA-sensing systems that is activated in response to …

Have mRNA vaccines sentenced DNA vaccines to death?

A Cagigi, B Douradinha - Expert Review of Vaccines, 2023 - Taylor & Francis
Introduction After receiving emergency approval during the COVID-19 pandemic, mRNA
vaccines have taken center stage in the quest to enhance future vaccination strategies for …

[图书][B] Understanding the role of the Parkinson's associated kinase LRRK2 in inflammation and infection

M Öberg - 2024 - gupea.ub.gu.se
The innate immune system, which mediates pathogen clearance and tissue healing,
requires tight regulation to avert self-destruction. The endo-lysosomal system is best known …