Tumor response to neoadjuvant chemoradiation (nCRT) with tumor downsizing and
downstaging has significantly impacted the number of patients considered to be appropriate …

Purpose The oncologic outcome of concurrent chemoradiotherapy (CCRT) after local
excision in patients with high-risk early rectal cancer as compared with radical operation has …

© 2023, Roeland Rombout Eppenga, The Netherlands. All rights reserved. No parts of this
thesis may be reproduced, stored in a retrieval system or transmitted in any form or by any …

The number of rectal cancer treatment options has increased substantially over the past
several decades, in parallel with an increased demand for organ preservation. Increasingly …

• Transanal endoscopic surgery techniques including trans-anal endoscopic microsurgery
(TEM) and transanal mini-mally invasive surgery (TAMIS) may improve surgical outcomes as …

[Background] To investigate the clinical safety and efficacy of local excision with
endovascular gastrointestinal anastomosis stapler (Endo-GIA) in the treatment of T2N0M0 …

First, several studies have shown that treatment modality, tumour distance from the anal
dentate line, vascular infiltration and perineural infiltration are strongly linked to tumour …

Local excision for a rectal tumor dates back to the early 1800s, with a report by Dr. Jacques
Lisfranc describing excision of a benign rectal mass in the lower rectum.[1] This approach is …

Se ha incrementado la utilización de la resección local (RL) en el cáncer de recto inicial
como alternativa a la resección radical (RR). Pese a ofrecer una menor morbilidad, aún …

Background: After local excision of early rectal cancer, clinical dilemmas arise when
balancing the risks of recurrence and treatment related morbidity, but few data are available …