Systematic review of pharmacokinetics and potential pharmacokinetic interactions of flavonolignans from silymarin

V Tvrdý, J Pourová, E Jirkovský, V Křen… - Medicinal Research …, 2021 - Wiley Online Library
Silymarin is an extract from the seeds (fruits) of Silybum marianum that contains
flavonolignans and flavonoids. Although it is frequently used as a hepatoprotective agent, its …

Intestinal and hepatocellular transporters: therapeutic effects and drug interactions of herbal supplements

B Stieger, ZM Mahdi, W Jäger - Annual review of pharmacology …, 2017 - annualreviews.org
Herbal supplements are generally considered safe; however, drug disposition is influenced
by the interactions of herbal supplements and food constituents with transport and metabolic …

Glycyrrhizin has a high likelihood to be a victim of drug–drug interactions mediated by hepatic organic anion‐transporting polypeptide 1B1/1B3

J Dong, OE Olaleye, R Jiang, J Li, C Lu… - British journal of …, 2018 - Wiley Online Library
Background and Purpose Intravenous glycyrrhizin, having anti‐inflammatory and
hepatoprotective properties, is incorporated into the management of liver diseases in China …

[HTML][HTML] Glycolysis aggravates methotrexate toxicity by fueling RFC1-controlled intestinal absorption in rheumatic rats

QH Wang, S Pan, K Yang, YJ Wu, XP Cheng… - Biomedicine & …, 2022 - Elsevier
Methotrexate (MTX) is a first line anti-rheumatic drug. This study was designed to investigate
the impact of rheumatoid arthritis (RA) conditions on its oral absorption, and clarify the …

Phytotherapy and Liver Disease

L Čalkić - Liver Cirrhosis-Debates and Current Challenges, 2019 - books.google.com
Hepatoprotective agents are medicines or dietary supplements that are used as an adjunct
to the treatment of acute and chronic viral hepatitis, liver cirrhosis, hepatocellular carcinoma …

Current trends in the prevention and treatment of liver diseases with phytopreparations

N Hristova, B Dobrev, D Dimitrova… - Varna medical …, 2019 - journals.mu-varna.bg
VMF_2019_pril. 3.indb Page 1 130 Варненски медицински форум, т. 8, 2019, приложение 3
МУ-Варна СЪВРЕМЕННИ ТЕНДЕНЦИИ ПРИ ПРОФИЛАКТИКА И ТЕРАПИЯ НА …

Editorial (Thematic Issue: Role of Drug Metabolism and its Mediated DDI in Drug Efficacy and Safety Part 2)

C Liu, X He - Current drug metabolism, 2015 - ingentaconnect.com
Cytochrome P450 (CYP450) enzymes are the most important metabolizing enzyme family
existing among all organs. A part from their role in the deactivation of most endogenous and …

Analýza rizik v logistické firmě pro distribuci farmaceutik

L Chromcová - 2017 - digilib.k.utb.cz
Cílem BP je řešení distribuce ve farmaceutické firmě (soucast logistickeho retezce) a
současně vyhledat a analyzovat rizika, ktera při tomto procesu vznikají. Tyto rizika vyhodnotit …