Functional recovery of injured peripheral neurons often remains incomplete, but the clinical
outcome can be improved by increasing the axonal growth rate. Adult transgenic …

Implications of GSK3 activity for axon regeneration are often inconsistent, if not controversial.
Sustained GSK3 activity in GSK3S/A knock-in mice reportedly accelerates peripheral nerve …

Treatments accelerating axon regeneration in the nervous system are still clinically
unavailable. However, parthenolide promotes adult sensory neurons' axon growth in culture …

Peripheral nerve injury disease is a prevalent traumatic condition in current medical
practice. Despite the present treatment approaches, encompassing surgical sutures …

Both the establishment of neuronal polarity and axonal growth are crucial steps in the
development of the nervous system. The local translation of mRNAs in the axon provides …

Personalized management of neuropathic pain is an unmet clinical need due to
heterogeneity of the underlying aetiologies, incompletely understood pathophysiological …

The clinical “gold standard” technique for attempting to restore function to nerves with a gap
is to bridge the gap with sensory autografts. However, autografts induce good to excellent …

There are contradictory reports on the role of the serine/threonine kinase isoform glycogen
synthase kinase-3β (GSK3β) after injury to the central nervous system (CNS). Some report …

Treatments accelerating axon regeneration in the nervous system are still unavailable in the
clinic. However, in culture, parthenolide markedly promotes adult sensory neurons' axon …

Background Application of general anesthetics may induce neurotoxicity in dorsal root
ganglia (DRG) neurons. In this study, we examined the possible protective mechanism and …