Recent insights into the pathogenesis of pre-eclampsia

JM Roberts, KY Lain - Placenta, 2002 - Elsevier
Pre-eclampsia is more than pregnancy induced hypertension. The emerging view described
in this presentation is that pre-eclampsia is secondary to the interactions of reduced …

Leptin in pregnancy: an update

MC Henson, VD Castracane - Biology of reproduction, 2006 - academic.oup.com
Leptin influences satiety, adiposity, and metabolism and is associated with mechanisms
regulating puberty onset, fertility, and pregnancy in various species. Maternal …

Leptin in pregnancy

MC Henson, VD Castracane - Biology of reproduction, 2000 - academic.oup.com
Leptin is a polypeptide hormone that aids in the regulation of body weight and energy
homeostasis and is linked to a variety of reproductive processes in both animals and …

Leptin Production and Release in the Dually in VitroPerfused Human Placenta

K Linnemann, A Malek, R Sager… - The Journal of …, 2000 - academic.oup.com
There is clear evidence that the placenta produces leptin. However, it is still unclear to what
extent leptin is released into the maternal and the fetal circulation. The aim of our study was …

Leptin: a possible metabolic signal affecting reproduction

LJ Spicer - Domestic Animal Endocrinology, 2001 - Elsevier
Since its discovery in 1994, leptin, a protein hormone synthesized and secreted by adipose
tissue, has been shown to regulate feed intake in several species including sheep and pigs …

Placental leptin in normal, diabetic and fetal growth-retarded pregnancies

RG Lea, D Howe, LT Hannah… - Molecular human …, 2000 - academic.oup.com
Leptin expression in third trimester placenta (p) and leptin concentrations in umbilical cord
blood (cb) were investigated in normal pregnancies [n= 10 (p), 31 (cb)] and abnormal …

Physiological roles of the leptin endocrine system: differences between mice and humans

J Himms-Hagen - Critical reviews in clinical laboratory sciences, 1999 - Taylor & Francis
Leptin is a 16-kDa cytokine secreted in humans primarily but not exclusively by adipose
tissues. Its concentration in blood is usually proportional to body fat mass, but is higher in …

Role of leptin in pregnancy—a review

N Sagawa, S Yura, H Itoh, H Mise, K Kakui, D Korita… - Placenta, 2002 - Elsevier
Leptin is an adipocyte-derived hormone that decreases food intake and body weight via its
receptor in the hypothalamus. In rodents, it also modulates glucose metabolism by …

Leptin as a breast milk component for the prevention of obesity

M Palou, C Picó, A Palou - Nutrition reviews, 2018 - academic.oup.com
Leptin ingested as a component of breast milk is increasingly recognized to play a role in the
postnatal programming of a healthy phenotype in adulthood. Besides its primary function in …

Physiologic and molecular alterations in carbohydrate metabolism during pregnancy and gestational diabetes mellitus

H Yamashita, J Shao, JE Friedman - Clinical obstetrics and …, 2000 - journals.lww.com
Pregnancy is characterized as a diabetogenic state. Although 95–97% of all women retain
normal glucose tolerance, approximately 3–5% develop gestational diabetes mellitus …