The contribution of preclinical magnetic resonance imaging and spectroscopy to Huntington's disease

JB Pérot, E Brouillet, J Flament - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Huntington's disease is an inherited disorder characterized by psychiatric, cognitive, and
motor symptoms due to degeneration of medium spiny neurons in the striatum. A prodromal …

Neuroimaging to Facilitate Clinical Trials in Huntington's Disease: Current Opinion from the EHDN Imaging Working Group

NZ Hobbs, M Papoutsi, A Delva… - Journal of …, 2024 - content.iospress.com
Neuroimaging is increasingly being included in clinical trials of Huntington's disease (HD)
for a wide range of purposes from participant selection and safety monitoring, through to …

[HTML][HTML] HD-DRUM, a Tablet-Based Drumming Training App Intervention for People With Huntington Disease: App Development Study

C Metzler-Baddeley, M Busse, C Drew… - JMIR Formative …, 2023 - formative.jmir.org
Background Huntington disease (HD) is a neurodegenerative condition that leads to
progressive loss of cognitive-executive and motor functions, largely due to basal ganglia …

[HTML][HTML] Diffusion MRI marks progressive alterations in fiber integrity in the zQ175DN mouse model of Huntington's disease

N Vidas-Guscic, J Van Rijswijk, J Van Audekerke… - Neurobiology of …, 2024 - Elsevier
Huntington's disease (HD) is a progressive neurodegenerative disease affecting motor and
cognitive abilities. Multiple studies have found white matter anomalies in HD-affected …

Progressive mitochondrial dysfunction of striatal synapses in R6/2 mouse model of Huntington's disease

MH Petersen, CW Willert, JV Andersen… - Journal of …, 2022 - content.iospress.com
Background: Huntington's disease (HD) is a neurodegenerative disorder characterized by
synaptic dysfunction and loss of white matter volume especially in the striatum of the basal …

[HTML][HTML] Differential tractography as a dynamic imaging biomarker: A methodological pilot study for Huntington's disease

JV Barrios-Martinez, DT Fernandes-Cabral… - NeuroImage: Clinical, 2022 - Elsevier
Huntington's disease (HD) is a neurodegenerative disorder characterized by motor,
psychiatric, and cognitive symptoms. Due to its diverse manifestations, the scientific …

HD-DRUM, a tablet-based drumming training application intervention for people with Huntington's Disease: Application development using an integrated knowledge …

C Metzler-Baddeley, M Busse-Morris… - Journal of Medical …, 2023 - orca.cardiff.ac.uk
ABSTRACT Background: Huntington's Disease (HD) is a neurodegenerative disease that
leads to the progressive loss of cognitive-executive and motor functions, largely due to basal …

Protocol for a randomised controlled unblinded feasibility trial of HD-DRUM: a rhythmic movement training application for cognitive and motor symptoms in people with …

V Ioakeimidis, M Busse, CJG Drew, P Pallmann… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Huntington's disease (HD) is an inherited neurodegenerative disease causing
progressive cognitive and motor decline, largely due to basal ganglia (BG) atrophy …

Protocol for a randomised controlled feasibility trial of HD-DRUM, a rhythmic movement training application for cognitive and motor symptoms in people with …

V Ioakeimidis, M Busse, C Drew, P Pallmann, D Jones… - medRxiv, 2023 - medrxiv.org
Introduction: Huntingtons disease (HD) is an inherited neurodegenerative disease causing
progressive cognitive and motor decline, largely due to basal ganglia (BG) atrophy …

Advances in the neuroimaging of motor disorders

EL Weil, MO Nakawah, JC Masdeu - Handbook of Clinical Neurology, 2023 - Elsevier
Neuroimaging is a valuable adjunct to the history and examination in the evaluation of motor
system disorders. Conventional imaging with computed tomography or magnetic resonance …