Microneedles for painless transdermal immunotherapeutic applications
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …
the treatment of various diseases. However, owing to the dynamic nature of the immune …
Transdermal drug delivery: innovative pharmaceutical developments based on disruption of the barrier properties of the stratum corneum
The skin offers an accessible and convenient site for the administration of medications. To
this end, the field of transdermal drug delivery, aimed at developing safe and efficacious …
this end, the field of transdermal drug delivery, aimed at developing safe and efficacious …
Transdermal microneedles for the programmable burst release of multiple vaccine payloads
Repeated bolus injections are associated with higher costs and poor compliance and can
hinder the implementation of global immunization campaigns. Here, we report the …
hinder the implementation of global immunization campaigns. Here, we report the …
Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies
The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies
and recombinant proteins, poses substantial challenges owing to their large size and …
and recombinant proteins, poses substantial challenges owing to their large size and …
Microneedles for drug and vaccine delivery
Microneedles were first conceptualized for drug delivery many decades ago, but only
became the subject of significant research starting in the mid-1990's when microfabrication …
became the subject of significant research starting in the mid-1990's when microfabrication …
Engineering microneedle patches for vaccination and drug delivery to skin
MR Prausnitz - Annual review of chemical and biomolecular …, 2017 - annualreviews.org
Microneedle patches (MNPs) contain arrays of solid needles measuring hundreds of
microns in length that deliver drugs and vaccines into skin in a painless, easy-to-use …
microns in length that deliver drugs and vaccines into skin in a painless, easy-to-use …
An overview of clinical and commercial impact of drug delivery systems
AC Anselmo, S Mitragotri - Journal of Controlled Release, 2014 - Elsevier
Drug delivery systems are widely researched and developed to improve the delivery of
pharmaceutical compounds and molecules. The last few decades have seen a marked …
pharmaceutical compounds and molecules. The last few decades have seen a marked …
Microneedles as the technique of drug delivery enhancement in diverse organs and tissues
AS Rzhevskiy, TRR Singh, RF Donnelly… - Journal of controlled …, 2018 - Elsevier
Microneedles is the technique of drug delivery enhancement, which was primarily designed
for facilitating percutaneous drug delivery. Started from the development of simple solid …
for facilitating percutaneous drug delivery. Started from the development of simple solid …
Advances in intranasal vaccine delivery: A promising non-invasive route of immunization
E Kehagia, P Papakyriakopoulou, G Valsami - Vaccine, 2023 - Elsevier
The importance of vaccination has been proven particularly significant the last three years,
as it is revealed to be the most efficient weapon for the prevention of several infections …
as it is revealed to be the most efficient weapon for the prevention of several infections …
Micro-scale devices for transdermal drug delivery
A Arora, MR Prausnitz, S Mitragotri - International journal of pharmaceutics, 2008 - Elsevier
Skin makes an excellent site for drug and vaccine delivery due to easy accessibility, immuno-
surveillance functions, avoidance of macromolecular degradation in the gastrointestinal tract …
surveillance functions, avoidance of macromolecular degradation in the gastrointestinal tract …