Arrhythmogenic cardiomyopathy
D Corrado, C Basso, DP Judge - Circulation research, 2017 - Am Heart Assoc
Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder, predisposing to
sudden cardiac death, particularly in young patients and athletes. Pathological features …
sudden cardiac death, particularly in young patients and athletes. Pathological features …
Molecular mechanisms of arrhythmogenic cardiomyopathy
KM Austin, MA Trembley, SF Chandler… - Nature Reviews …, 2019 - nature.com
Arrhythmogenic cardiomyopathy is a genetic disorder characterized by the risk of life-
threatening arrhythmias, myocardial dysfunction and fibrofatty replacement of myocardial …
threatening arrhythmias, myocardial dysfunction and fibrofatty replacement of myocardial …
Mechanotransduction in cardiac hypertrophy and failure
RC Lyon, F Zanella, JH Omens, F Sheikh - Circulation research, 2015 - Am Heart Assoc
Cardiac muscle cells have an intrinsic ability to sense and respond to mechanical load
through a process known as mechanotransduction. In the heart, this process involves the …
through a process known as mechanotransduction. In the heart, this process involves the …
'Hot phase'clinical presentation in arrhythmogenic cardiomyopathy
Aims The aim of this study is to evaluate the clinical features of patients affected by
arrhythmogenic cardiomyopathy (AC), presenting with chest pain and myocardial enzyme …
arrhythmogenic cardiomyopathy (AC), presenting with chest pain and myocardial enzyme …
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes
MS Nielsen, CJM van Opbergen… - Physiological …, 2023 - journals.physiology.org
The intercalated disc (ID) is a highly specialized structure that connects cardiomyocytes via
mechanical and electrical junctions. Although described in some detail by light microscopy …
mechanical and electrical junctions. Although described in some detail by light microscopy …
Extracellular vesicles from immortalized cardiosphere-derived cells attenuate arrhythmogenic cardiomyopathy in desmoglein-2 mutant mice
YN Lin, T Mesquita, L Sanchez, YH Chen… - European Heart …, 2021 - academic.oup.com
Aims Arrhythmogenic cardiomyopathy (ACM) is characterized by progressive loss of
cardiomyocytes, and fibrofatty tissue replacement. Extracellular vesicles (EVs) secreted by …
cardiomyocytes, and fibrofatty tissue replacement. Extracellular vesicles (EVs) secreted by …
The cardiac desmosome and arrhythmogenic cardiomyopathies: from gene to disease
M Delmar, WJ McKenna - Circulation research, 2010 - Am Heart Assoc
Intercellular communication is essential for proper cardiac function. Mechanical and
electrical activity need to be synchronized so that the work of individual myocytes transforms …
electrical activity need to be synchronized so that the work of individual myocytes transforms …
[HTML][HTML] Arrhythmogenic cardiomyopathy
K Pilichou, G Thiene, B Bauce, I Rigato… - Orphanet journal of rare …, 2016 - Springer
Arrhythmogenic cardiomyopathy (AC) is a heart muscle disease clinically characterized by
life-threatening ventricular arrhythmias and pathologically by an acquired and progressive …
life-threatening ventricular arrhythmias and pathologically by an acquired and progressive …
Pathophysiology of arrhythmogenic cardiomyopathy
Arrhythmogenic cardiomyopathy (AC) is a clinically and genetically heterogeneous disorder
of heart muscle that is associated with ventricular arrhythmias and risk of sudden cardiac …
of heart muscle that is associated with ventricular arrhythmias and risk of sudden cardiac …
Definition and treatment of arrhythmogenic cardiomyopathy: an updated expert panel report
PM Elliott, A Anastasakis, A Asimaki… - European journal of …, 2019 - Wiley Online Library
It is 35 years since the first description of arrhythmogenic right ventricular cardiomyopathy
(ARVC) and more than 20 years since the first reports establishing desmosomal gene …
(ARVC) and more than 20 years since the first reports establishing desmosomal gene …