Long-term angiotensin-converting enzyme (ACE) inhibition may reduce ischemic events in
patients with coronary artery disease, but whether it protects against acute ischemia or the …

The primary hemodynamic hallmark of essential hypertension is elevated systemic vascular
resistance that may be affected by increased sympathetic tone, activation of the renin …

Actions mediated by the renin-angiotensin system may be inhibited at various levels: renin
itself may be inhibited, angiotensin-I (A-1) conversion to angiotensin-II (A-II), or binding of A …

Since their introduction in clinical practice in 1980, ACE inhibitors have been found useful in
the treatment of hypertension and CHF. In hypertension, they are effective as monotherapy …

Progressive asymptomatic ventricular dilatation can occur following myocardial infarction
and severe ventricular dysfunction is often present by the time clinical congestive heart …

Ma anipulation of the renin-angiotensin system has evolved during the last few years from
an obscure line of biochemical research and pathophysiologic experimentation into a new …

The renin-angiotensin system acts systemically and locally to influence vascular tone, blood
volume, myocardial contractility, thromboresistance, and tissue responses to injury. ACE …

1. The circulating and tissue renin‐angiotensin systems (RAS) contribute importantly to
cardiovascular homeostasis. Systemic and/or local activation of the RAS is seen in many …

Hypertension and atherosclerotic cardiovascular disease represent major global health
problems. Practising physicians are challenged daily by patients suffering adverse …

The efficacy of benazepril, metoprolol OROS and their combination was evaluated in 29
patients (42 to 74 years of age) with chronic stable angina and documented coronary artery …