Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

In response to infection, macrophages adapt their metabolism rapidly to enhance glycolysis
and fuel specialized antimicrobial effector functions. Here we show that fungal melanin is an …

Aspergillus fumigatus is a worldwide-distributed saprophytic fungus and the major cause of
invasive aspergillosis. This fungus can produce two types of melanin …

Infections due to Aspergillus species are an acute threat to human health; members of the
Aspergillus section Fumigati are the most frequently occurring agents, but depending on the …

Lipid rafts form signaling platforms on biological membranes with incompletely
characterized role in immune response to infection. Here we report that lipid-raft …

Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

Aspergillus fumigatus is the most important mould pathogen in immunosuppressed patients.
Suboptimal clearance of inhaled spores results in the colonisation of the lung airways by …

The prevalence of fungal diseases is increasing on a global scale, ranging from acute to
systemic infections caused by commensal or pathogenic microorganisms, often associated …

真菌黑色素在真菌抵抗外界理化损伤及宿主的免疫杀伤过程中起重要作用,
是真菌重要的毒力因子. 巨噬细胞是抗真菌固有免疫的一线细胞, 探讨真菌黑色素与巨噬细胞的 …