[HTML][HTML] What makes a multidisciplinary medication review and deprescribing intervention for older people work well in primary care? A realist review and synthesis

E Radcliffe, R Servin, N Cox, S Lim, QY Tan, C Howard… - BMC geriatrics, 2023 - Springer
Background A third of older people take five or more regular medications (polypharmacy).
Conducting medication reviews in primary care is key to identify and reduce/stop …

How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits

C Sirois, M Gosselin, C Laforce… - Basic & Clinical …, 2024 - Wiley Online Library
Some meta‐analyses suggest that deprescribing may reduce mortality. Our aim was to
determine the underlying factors contributing to this observed reduction. We analysed data …

Clinical decision‐making in benzodiazepine deprescribing by healthcare providers vs. AI‐assisted approach

I Bužančić, D Belec, M Držaić, I Kummer… - British journal of …, 2024 - Wiley Online Library
Aims The aim of this study was to compare the clinical decision‐making for benzodiazepine
deprescribing between a healthcare provider (HCP) and an artificial intelligence (AI) chatbot …

Deprescribing medications among patients with multiple prescribers: A socioecological model

A Silva Almodóvar, MS Keller, J Lee… - Journal of the …, 2024 - Wiley Online Library
Deprescribing is the intentional dose reduction or discontinuation of a medication. The
development of deprescribing interventions should take into consideration important …

Survey content validation evaluating the dissemination and implementation of deprescribing guidelines

CHJ Cheng, AV Langford, D Gnjidic… - Basic & Clinical …, 2024 - Wiley Online Library
Background Policies, protocols and processes within organisations can facilitate or hinder
guideline adoption. There is limited knowledge on the strategies used by organisations to …

Deprescribing in older adults with polypharmacy

A Hung, YH Kim, JM Pavon - bmj, 2024 - bmj.com
Polypharmacy is common in older adults and is associated with adverse drug events,
cognitive and functional impairment, increased healthcare costs, and increased risk of frailty …

The effect of deprescribing interventions on mortality and health outcomes in older people: An updated systematic review and meta‐analysis

HW Quek, A Page, K Lee, G Lee… - British Journal of …, 2024 - Wiley Online Library
Aims Previous systematic reviews suggest that deprescribing may improve survival,
particularly in frail older people. Evidence is rapidly accumulating, suggesting a need for an …

Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver …

P Denig, PJC Stuijt - Expert Review of Clinical Pharmacology, 2024 - Taylor & Francis
Introduction For people with type 2 diabetes and/or cardiovascular conditions, deprescribing
of glucose-lowering, blood pressure-lowering and/or lipid-lowering medication is …

Awareness, perspectives and practices of antibiotics deprescribing among physicians in Jordan: a cross-sectional study

R Abu-Farha, L Gharaibeh, KH Alzoubi… - … Policy and Practice, 2024 - Taylor & Francis
Background: Antibiotics have significantly reduced mortality and improved outcomes across
various medical fields; however, the rise of antibiotic resistance poses a major challenge …

How to reduce medications for people with multiple long term conditions

H Saul, S Cassidy, B Deeney, C Imison, J Reeve - BMJ, 2023 - bmj.com
The study Reeve J, Maden M, Hill R, et al. Deprescribing medicines in older people living
with multimorbidity and polypharmacy: the TAILOR evidence synthesis. Health Technol …