Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic
and epigenetic factors. With the development of new technologies (eg, single-cell RNA …

The amount of single-cell RNA-sequencing (scRNA-seq) data produced in the field of
human male reproduction has steadily increased. Transcriptional profiles of thousands of …

Background Spermatogenesis is an intricate developmental process during which
undifferentiated spermatogonia, containing spermatogonial stem cells (SSCs), undergo self …

Delayed family planning and increased parental age increases the risk for infertility and
impaired offspring health. While the impact of ageing on oogenesis is well studied, on …

Normal spermatogenesis and sperm function are crucial for male fertility. The effects of
healthy testicular aging and testicular premature aging on spermatogenesis, sperm function …

Traditional therapeutic interventions aim to restore male fertile potential or preserve sperm
viability in severe cases, such as semen cryopreservation, testicular tissue, germ cell …

Spermatogonial transplantation has been used as a standard assay for spermatogonial
stem cells (SSCs). After transplantation into the seminiferous tubules, SSCs transmigrate …

The spermatogonial stem cell (SSC) is a unique adult stem cell that requires tight
physiological regulation during development and adulthood. As the foundation of …

The curiosity to understand the mechanisms regulating transcription in pluripotent cells
resulted in identifying a unique transcription factor named Undifferentiated embryonic cell …

Although much has been published since the first cases of COVID-19, there remain
unanswered questions regarding SARS-CoV-2 impact on testes and the potential …