Rheumatoid arthritis is characterized by progressive joint inflammation and affects~ 1% of
the human population. We noted single-nucleotide polymorphisms (SNPs) in the apoptotic …

Bullous pemphigoid (BP) is a common autoimmune bullous disease affecting mainly the
elderly, with rising incidence due to increased life expectancy. This disease is characterized …

The aim of the treatment in autoimmune blistering diseases (AIBDs) is to induce and
maintain remission, which clinically corresponds to the cessation of new vesicle formation …

Bone remodeling is a physiological, dynamic process that mainly depends on the functions
of 2 cell types: osteoblasts and osteoclasts. Emerging evidence suggests that complement …

Mammalian species contain an internal circadian (ie, 24-h) clock that is synchronized to the
day and night cycles. Large epidemiological studies, which are supported by carefully …

Epidermolysis bullosa acquisita (EBA) is a rare blistering skin disease induced by
autoantibodies directed against type VII collagen. The transfer of antibodies against murine …

The cellular and fluid phase-innate immune responses of many diseases predominantly
involve activated neutrophil granulocytes and complement factors. However, a comparative …

Ticks secrete hundreds to thousands of proteins into the feeding site, that presumably all
play important functions in the modulation of host defense mechanisms. The current review …

Bullous pemphigoid (BP) is an autoimmune bullous disease, characterized by
autoantibodies targeting BP180 and BP230. The role of interleukin (IL)‐36, a potent …

The complement system is an essential component of the innate immune response and
plays a vital role in host defense and inflammation. Dysregulation of the complement system …