The Sphingosine-1-Phosphate Receptor Modulator Fingolimod Aggravates Murine
Epidermolysis Bullosa Acquisita The Sphingosine-1-Phosphate Receptor Modulator …

Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that
may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that …

Purpose Cleft palate repair surgeries lack a regenerative reconstructive option and, in many
cases, develop complications including oronasal fistula (ONF). Our group has developed a …

Nomacopan, a drug originally derived from tick saliva, has dual functions of sequestering
leukotriene B 4 (LTB 4) and inhibiting complement component 5 (C5) activation …

Tumor cell-derived vesicles are released by tumor cells, have a phospholipid bilayer, and
are widely distributed in various biological fluids. In recent years, it has been found that …

FIGURE 1 Topical nomacopan attenuated conjunctivitis in EAC and decreased IL-9 in
CD4+T cells.(A, B) Clinical scores of eyes were compared with saline-treated controls.(C− F) …

Background The molecular mechanism of septic shock is unknown. We studied the
pathogenesis of septic shock and provide a novel strategy for treating and improving the …

Objective To provide an alternative therapeutic modality for rheumatoid arthritis (RA), a
novel bispecific antibody (BsAb) targeting human tumor necrosis factor α (TNF-α) and …

English Chronic hepatitis B virus (HBV) infection is one of the most common factors
associated with hepatocellular carcinoma (HCC). However, the pathogenesis of HBV …

L'infection chronique par le virus de l'hépatite B (VHB) est l'un des facteurs les plus
fréquemment associés au carcinome hépatocellulaire (CHC). Cependant, la pathogenèse …