Production of a bispecific antibody targeting TNF-α and C5a in Pichia pastoris and its therapeutic potential in rheumatoid arthritis

J Chen, Z He, Y Fan, X Zhou, L Li, M Liu - Biotechnology letters, 2020 - Springer
Objective To provide an alternative therapeutic modality for rheumatoid arthritis (RA), a
novel bispecific antibody (BsAb) targeting human tumor necrosis factor α (TNF-α) and …

Rôle des protéines HBe et HBc du virus de l'hépatite B dans l'hépatocarcinogenèse.

C Lefeuvre, A Ducancelle - Virologie, 2023 - search.ebscohost.com
English Chronic hepatitis B virus (HBV) infection is one of the most common factors
associated with hepatocellular carcinoma (HCC). However, the pathogenesis of HBV …

Role of hepatitis B virus e protein and core protein in hepatocarcinogenesis

C Lefeuvre, A Ducancelle - Virologie, 2023 - jle.com
L'infection chronique par le virus de l'hépatite B (VHB) est l'un des facteurs les plus
fréquemment associés au carcinome hépatocellulaire (CHC). Cependant, la pathogenèse …

[HTML][HTML] A look at the C3 and C5 proteins in the Covid-19

HD Mosquera-Daza - Actualidades Biológicas, 2021 - scielo.org.co
The emergency caused by the new SARS-CoV-2 virus, which causes the Covid-19 disease,
has triggered a global pandemic. One of the most characteristic factors of SARS-CoV-2 virus …

Identification immune-related biomarkers of ankylosing spondylitis based on bioinformatics analysis

D Li, R Cao, W Dong, M Cheng, X Pan, Z Hu, J Hao - 2023 - researchsquare.com
Objective: The aim of this study is to search for key genes in ankylosing spondylitis through
comprehensive bioinformatics analysis, thus providing some theoretical support for future …

[PDF][PDF] Modulation of Neutrophil Activity by Soluble Complement Cleavage Products—An In-Depth Analysis. Cells 2022, 11, 3297

L Wohlgemuth, AEP Stratmann, F Münnich, S Bernhard… - 2022 - opus4.kobv.de
The cellular and fluid phase-innate immune responses of many diseases predominantly
involve activated neutrophil granulocytes and complement factors. However, a comparative …

Identification of key proteins related to cashmere fibre diameter by integrated proteomics and bioinformatic analysis

C Zhang, Q Qin, Z Liu, Y Wang, M Lan, D Zhao, D Kong… - 2023 - researchsquare.com
Goat (Capra hircus) has always been a source of fibre for human use and holds an
important place in international high-end textiles. Fibre diameter is the most concerned …

[PDF][PDF] Novel Metformin Indications and Skin Disorders

RS Hussein, WK Abdelbasset, O Mahfouz - Biomedicine, 2022 - researchgate.net
Metformin is the first-line medication to increase insulin sensitivity in insulin-resistant
conditions such as type 2 diabetes, polycystic ovary syndrome, and obesity. However …

Autoimmune bullous diseases: insights into diagnosis and disease management

H Rashid - 2022 - research.rug.nl
Autoimmune blistering diseases (AIBDs) are a group of rare and chronic skin and mucosal
disorders caused by autoantibodies targeted against structural proteins of the desmosomal …

[PDF][PDF] Inflammatory and Post-inflammatory Nociception in a Model of Arthritis

B Allen - 2022 - kclpure.kcl.ac.uk
Pain associated with rheumatoid arthritis (RA) is described as one of the most debilitating
symptoms of the condition, often persisting when joint inflammation is pharmacologically …