[PDF][PDF] Explorative Untersuchung zur Expression von C5aR1 und C5aR2 in frühen Hautveränderungen von Patienten mit bullösen Pemphigoid

R Stahlkopf - zhb.uni-luebeck.de
Abbildung 4: Schematischer Ablauf der Komplementaktivierung. Die drei Aktivierungswege,
der klassische-, der Lektin-und der alternative Weg, führen zur Aktivierung von C3 und …

Dupilumab effectively and rapidly treats bullous pemphigoid by inhibiting the activities of multiple cell types

T Yan, Y Xie, Y Liu, Y Shan, X Wu, J Wang… - Frontiers in …, 2023 - frontiersin.org
Background Bullous pemphigoid (BP) is an autoimmune skin-blistering disease. Systemic
corticosteroids remain the first line treatment for moderate-to-severe BP with the potential for …

[PDF][PDF] Aus der Klinik für Dermatologie, Allergologie und Venerologie der Universität zu Lübeck Direktor: Prof. Dr. med. D. Zillikens

A Derenda-Hell - zhb.uni-luebeck.de
Die Epidermolysis bullosa acquisita (EBA), eine dem bullösem Pemphigoid ähnliche
Autoimmundermatose, die durch Autoantikörper charakterisiert ist, welche gegen Kollagen …

Coversin for the treatment of autoimmune blistering diseases

MA Nunn, B Abhyankar, CD Sadik - 2018 - Google Patents
WO2018193122A1 - Coversin for the treatment of autoimmune blistering diseases - Google
Patents WO2018193122A1 - Coversin for the treatment of autoimmune blistering diseases …

[PDF][PDF] Autoimmune bullous diseases

H Rashid - research.rug.nl
The first part of this thesis is focused on mucous membrane pemphigoid (MMP) in a broader
sense, encompassing aspects regarding the definition and appropriate nomenclature of …

[图书][B] Protumoral role of complement activation in murine sarcoma and skin cancer models

S Di Marco - 2020 - search.proquest.com
Cancer related inflammation (CRI) plays a fundamental role in fueling tumor appearance
and development. Despite the important contribution of complement activation to …

[PDF][PDF] The pathophysiological role of IL-17 in bullous pemphigoid

L Chakievska - 2020 - zhb.uni-luebeck.de
IL-17A acts as a critical regulatory molecule in several autoimmune and chronic
inflammatory diseases and is successfully targeted, eg in ankylosing spondylitis and …

Pemphigoid diseases: Insights in the nonbullous variant and disease management

A Lamberts - 2020 - research.rug.nl
Bullous pemphigoid (BP) is a bullous skin disease, mainly occurring at old age. It is
characterized by pruritus and blisters on the skin. The disease is caused by an autoimmune …

[PDF][PDF] Leukotriene B4 and Its Receptor in Experimental Autoimmune Uveitis and in Human Retinal Tissues

M Eskandarpour, YH Chen, MA Nunn, SE Coupland… - 2020 - researchgate.net
Nomacopan, a drug originally derived from tick saliva, has dual functions of sequestering
leukotriene B4 (LTB4) and inhibiting complement component 5 (C5) activation. It has been …

[HTML][HTML] Carboxypeptidase B Inhibits Over-activation of Anaphylatoxin-neutrophil Extracellular Trap Axis in COVID-19 Patients

Y Zhang, K Han, C Du, R Li, J Liu, H Zeng, L Zhu, A Li - 2020 - europepmc.org
Background: Thrombosis and coagulopathy are highly prevalent in severe patients with
COVID-19 and increase the risk of death. Immunothrombosis has recently been …