Pemphigoid diseases: Insights in the nonbullous variant and disease management

A Lamberts - 2020 - research.rug.nl
Bullous pemphigoid (BP) is a bullous skin disease, mainly occurring at old age. It is
characterized by pruritus and blisters on the skin. The disease is caused by an autoimmune …

[PDF][PDF] Leukotriene B4 and Its Receptor in Experimental Autoimmune Uveitis and in Human Retinal Tissues

M Eskandarpour, YH Chen, MA Nunn, SE Coupland… - 2020 - researchgate.net
Nomacopan, a drug originally derived from tick saliva, has dual functions of sequestering
leukotriene B4 (LTB4) and inhibiting complement component 5 (C5) activation. It has been …

[HTML][HTML] Carboxypeptidase B Inhibits Over-activation of Anaphylatoxin-neutrophil Extracellular Trap Axis in COVID-19 Patients

Y Zhang, K Han, C Du, R Li, J Liu, H Zeng, L Zhu, A Li - 2020 - europepmc.org
Background: Thrombosis and coagulopathy are highly prevalent in severe patients with
COVID-19 and increase the risk of death. Immunothrombosis has recently been …

Identification and pathophysiological roles of LTB4 receptors BLT1 and BLT2

Y Ishii, T Okuno, T Yokomizo - Lipid Signaling and Metabolism, 2020 - Elsevier
Abstract Leukotriene B 4 (LTB 4), a lipid mediator derived from arachidonic acid, is a
chemoattractant for inflammatory leukocytes. We previously identified two receptors for LTB …

[PDF][PDF] Discussion and future perspectives

A Lamberts - Pemphigoid diseases: insights in the nonbullous …, 2020 - research.rug.nl
Pemphigoid-specific autoantibodies in healthy individuals Several studies have detected
pemphigoid-specific IgG autoantibodies in the serum of nondiseased people. 1–3 In chapter …

Rôle du facteur de transcription Nrf2 dans la régulation des fonctions du neutrophile in vitro et dans l'allergie cutanée

D Helou - 2018 - theses.hal.science
Les neutrophiles constituent une première ligne de défense contre les agents infectieux. En
revanche, leur activation incontrôlée peut exacerber certaines pathologies inflammatoires …

関節内インビボイメージングを用いた関節炎病態の解明

宮部斉重, 岩井佳子 - 日本医科大学医学会雑誌, 2020 - jstage.jst.go.jp
免疫細胞の遊走は体内へ侵入した病原体を駆除するために重要な生体防御機構であり,
この制御機構は様々な Chemoattractant 分子によって精密に制御されている …

[引用][C] 过敏毒素C5a 在痛风性关节炎患者中的表达及意义

刘静, 罗釆南, 王丹, 陈勇, 袁佳利, 罗雄燕 - 中国免疫学杂志, 2021