Background Severe dengue is a life-threatening complication; rapid identification of these
cases, followed by adequate management is crucial to improve the clinical prognosis …

Dengue counts among the most commonly encountered arboviral diseases, representing
the fastest spreading tropical illness in the world. It is prevalent in 128 countries, and each …

Summary Background On Nov 11, 2015, the Brazilian Ministry of Health declared a Public
Health Emergency of National Concern in response to an increased number of …

Abstract Background In Colombia, the dengue virus (DENV) has been endemic for decades,
and with the recent entry of the chikungunya virus (CHIKV)(2014) and the Zika virus …

Objectives Dengue infection is a growing public health problem, with the number of reported
cases increasing in the Americas and worldwide. This review characterized the …

Background Neglected Tropical Diseases (NTDs) are important causes of morbidity,
disability, and mortality among poor and vulnerable populations in several countries …

CD8+ T cells play an important role in controlling Flavivirus infection, including Zika virus
(ZIKV). Here, we have identified 25 HLA-B* 0702-restricted epitopes and 1 HLA-A* 0101 …

Importance The Zika virus (ZIKV) might cause microcephaly and ophthalmoscopic findings
in infants of mothers infected during pregnancy. Objective To assess and identify possible …

Background In 2015, high rates of microcephaly were reported in Northeast Brazil following
the first South American Zika virus (ZIKV) outbreak. Reported microcephaly rates in other …

Background The co-circulation of flaviviruses in tropical regions has led to the hypothesis
that immunity generated by a previous dengue infection could promote severe disease …