Immunopathological similarities between COVID-19 and influenza: Investigating the consequences of Co-infection

H Khorramdelazad, MH Kazemi, A Najafi… - Microbial …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been a global public health emergency since …

[HTML][HTML] Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine

H Ghaffari, A Tavakoli, A Moradi, A Tabarraei… - Journal of biomedical …, 2019 - Springer
Background Currently available anti-influenza drugs are often associated with limitations
such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing …

[HTML][HTML] Zinc and respiratory viral infections: important trace element in anti-viral response and immune regulation

F Sadeghsoltani, I Mohammadzadeh, MM Safari… - Biological trace element …, 2021 - Springer
Influenza viruses, respiratory syncytial virus (RSV), and SARS-COV2 are among the most
dangerous respiratory viruses. Zinc is one of the essential micronutrients and is very …

Protein aggregation and mitigation strategy in low pH viral inactivation for monoclonal antibody purification

W Jin, Z Xing, Y Song, C Huang, X Xu, S Ghose, ZJ Li - MAbs, 2019 - Taylor & Francis
Significant amounts of soluble product aggregates were observed during low-pH viral
inactivation (VI) scale-up for an IgG4 monoclonal antibody (mAb IgG4-N1), while small-scale …

Soluble expression of single-chain variable fragment (scFv) in Escherichia coli using superfolder green fluorescent protein as fusion partner

M Liu, B Wang, F Wang, Z Yang, D Gao… - Applied microbiology …, 2019 - Springer
Single-chain variable fragment (scFv) has great prospect in medical therapies and
diagnostic applications due to its binding affinity and low immunogenicity. However, the …

[HTML][HTML] Human antibodies to VP4 inhibit replication of enteroviruses across subgenotypes and serotypes, and enhance host innate immunity

S Phanthong, J Densumite, W Seesuay… - Frontiers in …, 2020 - frontiersin.org
Hand, foot, and mouth disease (HFMD) is a highly contagious disease that usually affects
infants and young children (< 5 years). HFMD outbreaks occur frequently in the Asia-Pacific …

[HTML][HTML] Preparation and directed evolution of anti-ciprofloxacin scFv for immunoassay in animal-derived food

F Wang, N Li, Y Zhang, X Sun, M Hu, Y Zhao, J Fan - Foods, 2021 - mdpi.com
An immunized mouse phage display scFv library with a capacity of 3.34× 109 CFU/mL was
constructed and used for screening of recombinant anti-ciprofloxacin single-chain antibody …

[HTML][HTML] Human Single-Chain Antibodies That Neutralize Elastolytic Activity of Pseudomonas aeruginosa LasB

S Santajit, T Kong-Ngoen, M Chongsa-Nguan… - Pathogens, 2021 - mdpi.com
LasB (elastase/pseudolysin) is an injurious zinc-metalloprotease secreted by the infecting
Pseudomonas aeruginosa. LasB is recognized as the bacterial key virulence factor for …

Therapeutic antibodies: an overview

G Houen - Therapeutic Antibodies: Methods and Protocols, 2022 - Springer
Polyclonal immunoglobulin (Ig) preparations have been used for several decades for
treatment of primary and secondary immunodeficiencies and for treatment of some infections …

[HTML][HTML] Human Superantibodies to 3CLpro Inhibit Replication of SARS-CoV-2 across Variants

K Glab-Ampai, K Kaewchim, T Saenlom… - International Journal of …, 2022 - mdpi.com
Broadly effective and safe anti-coronavirus agent is existentially needed. Major protease
(3CLpro) is a highly conserved enzyme of betacoronaviruses. The enzyme plays pivotal role …