International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …
therapeutics and various drugs in development. Their diversity of structure and function …
A review of central 5-HT receptors and their function
NM Barnes, T Sharp - Neuropharmacology, 1999 - Elsevier
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
Dopamine receptors: molecular biology, biochemistry and behavioural aspects
DM Jackson, A Westlind-Danielsson - Pharmacology & therapeutics, 1994 - Elsevier
The description of new dopamine (DA) receptor subtypes, D1-(D1 and D5) and D2-like
(D2A, D2B, D3, D4), has given an impetus to DA research. While selective agonists and …
(D2A, D2B, D3, D4), has given an impetus to DA research. While selective agonists and …
Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain
K Varnäs, C Halldin, H Hall - Human brain mapping, 2004 - Wiley Online Library
Several neurochemical in vitro and in vivo imaging studies have been aimed at
characterizing the localization of serotonin receptors and transporters in the human brain. In …
characterizing the localization of serotonin receptors and transporters in the human brain. In …
Localization of 5-HT1B, 5-HT1Dα, 5-HT1E and 5-HT1F receptor messenger RNA in rodent and primate brain
AT Bruinvels, B Landwehrmeyer, EL Gustafson… - …, 1994 - Elsevier
In situ hybridization histochemistry (ISHH) was used to study the distribution of various 5-HT
1 receptor messenger RNAs (mRNA) in the mammalian nervous system. Since the cDNAs …
1 receptor messenger RNAs (mRNA) in the mammalian nervous system. Since the cDNAs …
The mouse 5-hydroxytryptamine 1B receptor is localized predominantly on axon terminals
U Boschert, DA Amara, L Segu, R Hen - Neuroscience, 1994 - Elsevier
The 5-hydroxytryptamine 1B receptor is a serotonin receptor subtype which is expressed
predominantly in the basal ganglia. It has been suggested to play a role in movement and …
predominantly in the basal ganglia. It has been suggested to play a role in movement and …
Serotonin 5-HT1A agonist improves motor complications in rodent and primate parkinsonian models
F Bibbiani, JD Oh, TN Chase - Neurology, 2001 - AAN Enterprises
Background: Serotoninergic transmission in the basal ganglia is known to influence
dopaminergic mechanisms and motor function. Objective: To evaluate the possibility that …
dopaminergic mechanisms and motor function. Objective: To evaluate the possibility that …
Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature
GR Martin, PPA Humphrey - Neuropharmacology, 1994 - Elsevier
With the increasing number of 5-HT receptors recently identified, using molecular biology
techniques, the classification of 5-HT receptors is under review. An integrated approach is …
techniques, the classification of 5-HT receptors is under review. An integrated approach is …
Agonist and antagonist actions of yohimbine as compared to fluparoxan at α2‐adrenergic receptors (AR) s, serotonin (5‐HT) 1A, 5‐HT1B, 5‐HT1D and dopamine D2 …
MJ Millan, A Newman‐Tancredi, V Audinot… - Synapse, 2000 - Wiley Online Library
Herein, we evaluate the interaction of the α2‐AR antagonist, yohimbine, as compared to
fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation …
fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation …
Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.
RL Weinshank, JM Zgombick… - Proceedings of the …, 1992 - National Acad Sciences
The serotonin 1D (5-HT1D) receptor is a pharmacologically defined binding site and
functional receptor site. Observed variations in the properties of 5-HT1D receptors in …
functional receptor site. Observed variations in the properties of 5-HT1D receptors in …