Pan-genomics can encompass most of the genetic diversity of a species or population and
has proved to be a powerful tool for studying genomic evolution and the origin and …

Medicinal plants are the main source of natural metabolites with specialised
pharmacological activities and have been widely examined by plant researchers. Numerous …

Butylphthalide is one of the first-line drugs for ischemic stroke therapy, while no biosynthetic
enzyme for butylphthalide has been reported. Here, we present a haplotype-resolved …

Globally, medicinal plant natural products (PNPs) are a major source of substances used in
traditional and modern medicine. As we human race face the tremendous public health …

Plant species have evolved diverse metabolic pathways to effectively respond to internal
and external signals throughout their life cycle, allowing adaptation to their sessile and …

Glycerol-3-phosphate acyltransferase (GPAT) catalyzes the first step in triacylglycerol (TAG)
biosynthesis. However, GPAT members and their functions remain poorly understood in …

Perilla frutescens (Lamiaceae) is an important herbal plant with hundreds of bioactive
chemicals, among which perillaldehyde and rosmarinic acid are the two major bioactive …

Perilla (Perilla frutescens) is a potential specific oilseed crop with an extremely high α-
linolenic acid (ALA) content in its seeds. AP2/ERF transcription factors (TFs) play important …

The ent-kaurenoids (eg, oridonin and enmein) from the Isodon genus (Lamiaceae) are one
class of diterpenoids with rich structural diversity and intriguing pharmaceutical activity. In …

The “genomic shock” hypothesis posits that unusual challenges to genome integrity such as
whole genome duplication may induce chaotic genome restructuring. Decades of research …