Recent reviews have emphasized the need for a health equity agenda in genomics
research. To ensure that genomic discoveries can lead to improved health outcomes for all …

Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …

Purpose Three genetic conditions—hereditary breast and ovarian cancer syndrome, Lynch
syndrome, and familial hypercholesterolemia—have tier 1 evidence for interventions that …

Genetic testing for prostate cancer is rapidly growing and is increasingly being driven by
precision medicine. Rates of germline pathogenic variants have been reported in up to 15 …

Understanding population health disparities is an essential component of equitable
precision health efforts. Epidemiology research often relies on definitions of race and …

Black people have a higher incidence of colorectal cancer and worse survival rates when
compared with white people. Comprehensive genomic profiling was performed in 46,140 …

Cadmium (Cd) is an environmental toxicant of worldwide public health significance. Diet is
the main non-workplace Cd exposure source other than passive and active smoking. The …

Background Population-based genomic screening has the predicted ability to reduce
morbidity and mortality associated with medically actionable conditions. However, much …

Studies in human genetics deal with a plethora of human genome sequencing data that are
generated from specimens as well as available on public domains. With the development of …

Exome and genome sequencing are increasingly utilized in research studies and clinical
care and can provide clinically relevant information beyond the initial intent for sequencing …