[HTML][HTML] Citric acid cross-linking of a hydrogel from Aloe vera (Aloe barbadensis M.) engenders a pH-responsive, superporous, and smart material for drug delivery

J Irfan, A Ali, MA Hussain, MT Haseeb… - RSC …, 2024 - pubs.rsc.org
The current research work is based on the evaluation of a citric acid (CA) cross-linked Aloe
vera (Aloe barbadensis M.) leaf hydrogel (CL-ALH) for pH-dependent and sustained drug …

[HTML][HTML] A pH responsive and superporous biocomposite hydrogel of Salvia spinosa polysaccharide-co-methacrylic acid for intelligent drug delivery

A Ali, MT Haseeb, MA Hussain, UR Tulain… - RSC …, 2023 - pubs.rsc.org
Herein, a drug delivery system (SSH-co-MAA) based on the mucilage from seeds of Salvia
spinosa (SSH; polymer) and methacrylic acid (MAA; monomer) is introduced for the …

Revolutionizing colon cancer therapy by site-specific 5-fluorouracil delivery with novel stimuli-responsive mucoadhesive hydrogel: Optimization via response surface …

H Hanan, F Pervaiz, M Ijaz, SM Javaid… - Journal of Drug Delivery …, 2024 - Elsevier
fluorouracil (FU) is the key option of systemic therapy for advanced metastatic colon cancer
but has a cytotoxic impact on normal cells after intravenous administration therefore the …

A superabsorbent and pH-responsive copolymer-hydrogel based on acemannan from Aloe vera (Aloe barbadensis M.): A smart material for drug delivery

J Irfan, A Ali, MA Hussain, MT Haseeb… - International Journal of …, 2024 - Elsevier
Combining natural polysaccharides with synthetic materials improves their functional
properties which are essential for designing sustained-release drug delivery systems. In this …

The effect of deoxycholic acid-based hydrogels on hepatic, muscle and pancreatic beta cells

B Kovacevic, M Jones, SR Wagle, CM Ionescu… - Therapeutic …, 2024 - Future Science
Aim: The aim of this study is to test the biocompatibility of hydrogels with polysaccharides
and bile acids on three murine cell lines. Materials & methods: Novel hydrogels containing …

A pH-responsive Artemisia vulgaris mucilage-co-acrylic acid hydrogel: Synthesis, characterization, controlled drug release, toxicity studies, and MRI

M Farid-ul-Haq, MA Hussain, A Ali, MT Haseeb… - Journal of Drug Delivery …, 2024 - Elsevier
Herein, the focus of this research is to develop a novel pH-responsive and non-toxic
hydrogel via free radical polymerization of Artemisia vulgaris seed mucilage/hydrogel (AVH) …

In-vitro drug release and stability assessment of tailored levan–chitosan biocomposite hydrogel

B Veerapandian, TKR Selvaraj, SR Shanmugam… - Iranian Polymer …, 2024 - Springer
An oxidized levan–chitosan (OLC) cross-linked hydrogel, a 3D network polymeric material,
was prepared. Spectroscopic techniques confirmed the oxidation of levan and imine bond …

[HTML][HTML] Grafted tamarind kernel polysaccharide based Al3+ cross-linked hydrogel matrices for sustained release of drug in the gastrointestinal milieu

A Saha, K Mukherjee, B Ghosh, TK Giri - Pharmaceutical Science Advances, 2024 - Elsevier
Ionically cross-linked hydrogel serves as an excellent matrix material for the sustained
delivery of drugs. Tablets prepared with tamarind kernel polysaccharide (TKP) as the sole …

[PDF][PDF] ACUTE TOXICITY STUDIES OF METHACRYLIC ACID BASED COMPOSITE HYDROGEL OF SALVIA SPINOSA SEED MUCILAGE: A POTENTIAL NON-TOXIC …

A Ali, MA Hussain, MT Haseeb… - Cellulose …, 2024 - cellulosechemtechnol.ro
Safety evaluation of a newly designed polymeric drug delivery system (DDS), with/without
the addition of active pharmaceutical ingredients (APIs), is now mandatory for their …