[HTML][HTML] Carbapenem-Resistant Klebsiella pneumoniae: Virulence Factors, Molecular Epidemiology and Latest Updates in Treatment Options

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2023 - mdpi.com
Klebsiella pneumoniae is a Gram-negative opportunistic pathogen responsible for a variety
of community and hospital infections. Infections caused by carbapenem-resistant K …

Epidemiology and diagnostics of carbapenem resistance in gram-negative bacteria

P Nordmann, L Poirel - Clinical Infectious Diseases, 2019 - academic.oup.com
Carbapenem resistance in gram-negative bacteria has caused a global epidemic that
continues to grow. Although carbapenemase-producing Enterobacteriaceae have received …

Identification of novel mobile colistin resistance gene mcr-10

C Wang, Y Feng, L Liu, L Wei, M Kang… - Emerging microbes & …, 2020 - Taylor & Francis
Mobile colistin resistance (mcr) genes represent an emerging challenge. Here we describe
a novel mcr gene, mcr-10, on an IncFIA plasmid of an Enterobacter roggenkampii clinical …

[HTML][HTML] Mechanisms of action of carbapenem resistance

C Aurilio, P Sansone, M Barbarisi, V Pota, LG Giaccari… - Antibiotics, 2022 - mdpi.com
Carbapenem antibiotics are the most effective antimicrobials for the treatment of infections
caused by the most resistant bacteria. They belong to the category of β-lactams that include …

NDM metallo-β-lactamases and their bacterial producers in health care settings

W Wu, Y Feng, G Tang, F Qiao… - Clinical microbiology …, 2019 - Am Soc Microbiol
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

Antimicrobial resistance

L Morrison, TR Zembower - Gastrointestinal Endoscopy …, 2020 - giendo.theclinics.com
Given recent media attention, it would be easy to assume that antimicrobial resistance is a
new problem; however, antimicrobial resistance has existed well before antimicrobials were …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

[HTML][HTML] Carbapenem resistance: a review

FS Codjoe, ES Donkor - Medical Sciences, 2017 - mdpi.com
Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Antibiotic resistance in hospital-acquired ESKAPE-E infections in low-and lower-middle-income countries: a systematic review and meta-analysis

O Ayobami, S Brinkwirth, T Eckmanns… - Emerging microbes & …, 2022 - Taylor & Francis
Antimicrobial resistance (AMR) and hospital-acquired infections (HAIs) are global health
challenges. The burden of antibiotic resistance in HAIs is still unclear in low-and lower …

[HTML][HTML] Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii

M Hamidian, SJ Nigro - Microbial genomics, 2019 - microbiologyresearch.org
Acinetobacter baumannii is a nosocomial pathogen that has emerged as a global threat
because of high levels of resistance to many antibiotics, particularly those considered to be …