Full-length circular RNA profiling by nanopore sequencing with CIRI-long

L Hou, J Zhang, F Zhao - Nature Protocols, 2023 - nature.com
Circular RNAs (circRNAs) have important roles in regulating developmental processes and
disease progression. As most circRNA sequences are highly similar to their cognate linear …

jMorp: Japanese Multi-Omics Reference Panel update report 2023

S Tadaka, J Kawashima, E Hishinuma… - Nucleic Acids …, 2024 - academic.oup.com
Modern medicine is increasingly focused on personalized medicine, and multi-omics data is
crucial in understanding biological phenomena and disease mechanisms. Each ethnic …

GWAS Central: an expanding resource for finding and visualising genotype and phenotype data from genome-wide association studies

T Beck, T Rowlands, T Shorter… - Nucleic Acids …, 2023 - academic.oup.com
The GWAS Central resource gathers and curates extensive summary-level genome-wide
association study (GWAS) data and puts a range of user-friendly but powerful website tools …

[HTML][HTML] Recent positive selection signatures reveal phenotypic evolution in the Han Chinese population

H Luo, P Zhang, W Zhang, Y Zheng, D Hao, Y Shi… - Science Bulletin, 2023 - Elsevier
Characterizing natural selection signatures and relationships with phenotype spectra is
important for understanding human evolution and both biological and pathological …

Innovative computational tools provide new insights into the polyploid wheat genome

Y Chen, W Wang, Z Yang, H Peng, Z Ni, Q Sun, W Guo - Abiotech, 2024 - Springer
Bread wheat (Triticum aestivum) is an important crop and serves as a significant source of
protein and calories for humans, worldwide. Nevertheless, its large and allopolyploid …

SilkMeta: a comprehensive platform for sharing and exploiting pan-genomic and multi-omic silkworm data

K Lu, Y Pan, J Shen, L Yang, C Zhan… - Nucleic Acids …, 2024 - academic.oup.com
The silkworm Bombyx mori is a domesticated insect that serves as an animal model for
research and agriculture. The silkworm super-pan-genome dataset, which we published last …

Repeated co-option of HMG-box genes for sex determination in brown algae and animals

R Luthringer, M Raphalen, C Guerra, S Colin… - Science, 2024 - science.org
In many eukaryotes, genetic sex determination is not governed by XX/XY or ZW/ZZ systems
but by a specialized region on the poorly studied U (female) or V (male) sex chromosomes …

Integration of yeast episomal/integrative plasmid causes genotypic and phenotypic diversity and improved sesquiterpene production in metabolically engineered …

B Peng, SJ Weintraub, Z Lu, S Evans… - ACS Synthetic …, 2023 - ACS Publications
The variability in phenotypic outcomes among biological replicates in engineered microbial
factories presents a captivating mystery. Establishing the association between phenotypic …

AnnoView enables large-scale analysis, comparison, and visualization of microbial gene neighborhoods

X Wei, H Tan, B Lobb, W Zhen, Z Wu… - Briefings in …, 2024 - academic.oup.com
The analysis and comparison of gene neighborhoods is a powerful approach for exploring
microbial genome structure, function, and evolution. Although numerous tools exist for …

Multi-locus genome-wide association study of chickpea reference set identifies genetic determinants of Pratylenchus thornei resistance

S Channale, JP Thompson, RK Varshney… - Frontiers in plant …, 2023 - frontiersin.org
Pratylenchus thornei is an economically important species of root-lesion nematode
adversely affecting chickpea (Cicer arietinum) yields globally. Integration of resistant crops …