Cancer cell plasticity: From cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance

GR Bhat, I Sethi, HQ Sadida, B Rah, R Mir… - Cancer and Metastasis …, 2024 - Springer
Cancer is a complex disease displaying a variety of cell states and phenotypes. This
diversity, known as cancer cell plasticity, confers cancer cells the ability to change in …

The role of different immunocompetent cell populations in the pathogenesis of head and neck cancer—regulatory mechanisms of pro-and anti-cancer activity and their …

K Starska-Kowarska - Cancers, 2023 - mdpi.com
Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

KLF7 regulates super-enhancer-driven IGF2BP2 overexpression to promote the progression of head and neck squamous cell carcinoma

H Cai, J Liang, Y Jiang, Z Wang, H Li, W Wang… - Journal of Experimental …, 2024 - Springer
Background Head and neck squamous carcinoma (HNSCC) is known for its high
aggressiveness and susceptibility to cervical lymph node metastasis, which greatly …

[HTML][HTML] TMED family genes and their roles in human diseases

L Zhou, H Li, H Yao, X Dai, P Gao… - International Journal of …, 2023 - ncbi.nlm.nih.gov
The members of the transmembrane emp24 domain-containing protein (TMED) family are
summarized in human as four subfamilies, α (TMED 4, 9), β (TMED 2), γ (TMED1, 3, 5, 6, 7) …

TMED2/9/10 serve as biomarkers for poor prognosis in head and neck squamous carcinoma

W Gao, ZW Zhang, HY Wang, XD Li, WT Peng… - Frontiers in …, 2022 - frontiersin.org
Background: Head and neck squamous carcinoma (HNSC) is one of the most common
malignant tumors with high incidence and poor prognosis. Transmembrane emp24 …

Dietary carotenoids in head and neck cancer—molecular and clinical implications

K Starska-Kowarska - Nutrients, 2022 - mdpi.com
Head and neck cancer (HNC) is one of the most common cancers in the world according to
GLOBCAN. In 2018, it was reported that HNC accounts for approximately 3% of all human …

Deciphering the immune landscape of head and neck squamous cell carcinoma: A single-cell transcriptomic analysis of regulatory T cell responses to PD-1 blockade …

A Miraki Feriz, F Bahraini, A Khosrojerdi, S Azarkar… - PLoS …, 2023 - journals.plos.org
Immunotherapy is changing the Head and Neck Squamous Cell Carcinoma (HNSCC)
landscape and improving outcomes for patients with recurrent or metastatic HNSCC. A …

From Pixels to Diagnosis: Algorithmic Analysis of Clinical Oral Photos for Early Detection of Oral Squamous Cell Carcinoma

S Rabinovici-Cohen, N Fridman, M Weinbaum, E Melul… - Cancers, 2024 - mdpi.com
Simple Summary The early detection of oral squamous cell carcinoma (OSCC) is crucial
because the prognosis is significantly better when diagnosed in its initial stages as opposed …

Immune cells in head-and-neck tumor microenvironments

E Jumaniyazova, A Lokhonina, D Dzhalilova… - Journal of Personalized …, 2022 - mdpi.com
Head-and-neck cancers constitute a heterogeneous group of aggressive tumors with high
incidence and low survival rates, collectively being the sixth most prevalent cancer type …

Decisional conflict and decision regret in head and neck oncology: a systematic review and meta-analysis

AN Heirman, CR Arends, DVC de Jel… - … –Head & Neck …, 2024 - jamanetwork.com
Importance Head and neck cancer (HNC) often requires treatment with a major impact on
quality of life. Treatment decision-making is often challenging, as it involves balancing …