Ruthenium complex is an important compound group for antitumor drug research and
development. NAMI-A, KP1019, TLD1433 and other ruthenium complexes have entered …

Triple-negative breast cancer (TNBC), which lacks the expression of the three hormone
receptors (ie, estrogen receptor, progesterone receptor, and human epidermal growth factor …

The gut microbiota (GM) has been shown to be closely associated with the development of
colorectal cancer (CRC). However, the involvement of GM is CRC has mainly been …

The proliferation of targeted anticancer agents over the last two decades has revolutionized
cancer treatment and improved survival in many previously refractory malignancies …

Development of novel therapeutic agents that possess different anticancer mechanisms from
the traditional antitumor drugs is highly attractive as no medication can cure all types of …

Tumour relapse, chemotherapy resistance, and metastasis continue to be unsolved issues
in cancer therapy. A recent approach has been to scrutinise drugs used in the clinic for other …

Emerging evidence indicates that cancer cells can mimic characteristics of embryonic
development, promoting their development and progression. Cancer cells share features …

The non-receptor protein tyrosine phosphatases gene family (PTPNs) is involved in the
tumorigenesis and development of many cancers, but the role of PTPNs in acute myeloid …

Despite recent therapy advances and a better understanding of colon cancer biology, it
remains one of the major causes of death. The cancer stem cells, associated with the …

Cancer cells are characterized by uncontrolled growth, proliferation, and impaired
apoptosis. Tumour progression could be related to poor prognosis and due to this fact …