Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost
all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of …

The phenotypic heterogeneity and functional diversity of macrophages confer on them
complexed roles in the development and progression of kidney diseases. After kidney injury …

The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae …

Scarring of the kidney is a major public health concern, directly promoting loss of kidney
function. To understand the role of microRNA (miRNA) in the progression of kidney scarring …

BACKGROUND: Acute kidney injury (AKI) is common in hospitalized patients. The impact of
AKI on long-term outcomes is controversial. STUDY DESIGN: Systematic review and meta …

Abstract Epithelial-mesenchymal transition (EMT), a process by which differentiated
epithelial cells undergo a phenotypic conversion that gives rise to the matrix-producing …

Monocyte-derived macrophages can determine the outcome of the immune response and
whether this response contributes to tissue repair or mediates tissue destruction. In addition …

Cordycepin is the major bioactive component extracted from Cordyceps militaris. In recent
years, cordycepin has received increasing attention owing to its multiple pharmacological …

Chronic kidney diseases generally lead to renal fibrosis. Despite great progress having
been made in identifying molecular mediators of fibrosis, the mechanism that governs renal …

The contraction of granulation tissue from skin wounds was first described in the 1960s.
Later it was discovered that during tissue repair, fibroblasts undergo a change in phenotype …