[HTML][HTML] Exosomes: New players in cancer
The past decade has witnessed an exponential increase in research on exosomes. For
many years considered to be extracellular debris, exosomes are now considered important …
many years considered to be extracellular debris, exosomes are now considered important …
Exosomes derived from human primary and metastatic colorectal cancer cells contribute to functional heterogeneity of activated fibroblasts by reprogramming their …
Cancer‐associated fibroblasts (CAFs) are a heterogeneous population of activated
fibroblasts that constitute a dominant cellular component of the tumor microenvironment …
fibroblasts that constitute a dominant cellular component of the tumor microenvironment …
[HTML][HTML] Determinants and functions of CAFs secretome during cancer progression and therapy
J Linares, JA Marín-Jiménez… - Frontiers in Cell and …, 2021 - frontiersin.org
Multiple lines of evidence are indicating that cancer development and malignant
progression are not exclusively epithelial cancer cell-autonomous processes but may also …
progression are not exclusively epithelial cancer cell-autonomous processes but may also …
[HTML][HTML] Microvesicles and chemokines in tumor microenvironment: mediators of intercellular communications in tumor progression
X Bian, YT Xiao, T Wu, M Yao, L Du, S Ren, J Wang - Molecular cancer, 2019 - Springer
Increasing evidence indicates that the ability of cancer cells to convey biological information
to recipient cells within the tumor microenvironment (TME) is crucial for tumor progression …
to recipient cells within the tumor microenvironment (TME) is crucial for tumor progression …
Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression
Purpose: Human osteosarcoma is a genetically heterogeneous bone malignancy with poor
prognosis despite the employment of aggressive chemotherapy regimens. Because …
prognosis despite the employment of aggressive chemotherapy regimens. Because …
[HTML][HTML] Modeling cell communication in cancer with organoids: making the complex simple
Homotypic and heterotypic interactions between cells are of crucial importance in
multicellular organisms for the maintenance of physiological functions. Accordingly, changes …
multicellular organisms for the maintenance of physiological functions. Accordingly, changes …
[HTML][HTML] Biomarkers in cancer detection, diagnosis, and prognosis
Biomarkers are vital in healthcare as they provide valuable insights into disease diagnosis,
prognosis, treatment response, and personalized medicine. They serve as objective …
prognosis, treatment response, and personalized medicine. They serve as objective …
[HTML][HTML] The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications
H Zheng, Y Zhan, S Liu, J Lu, J Luo, J Feng… - Journal of Experimental & …, 2018 - Springer
Non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases,
and it is one of the leading causes of cancer death in both men and women worldwide due …
and it is one of the leading causes of cancer death in both men and women worldwide due …
[HTML][HTML] How cancer cells dictate their microenvironment: present roles of extracellular vesicles
Y Naito, Y Yoshioka, Y Yamamoto, T Ochiya - Cellular and Molecular Life …, 2017 - Springer
Intercellular communication plays an important role in cancer initiation and progression
through secretory molecules, including growth factors and cytokines. Recent advances have …
through secretory molecules, including growth factors and cytokines. Recent advances have …
Exosomal microRNAs as liquid biopsy biomarkers in prostate cancer
J Wang, J Ni, J Beretov, J Thompson, P Graham… - Critical reviews in …, 2020 - Elsevier
Prostate cancer (PCa) is the most commonly diagnosed solid-organ cancer in males. The
PSA testing may cause overdiagnosis and overtreatment for PCa patients. There is an …
PSA testing may cause overdiagnosis and overtreatment for PCa patients. There is an …