Extracellular vesicles (EVs), especially exosomes, are now well recognized as major ways
by which cancer cells interact with each other and stromal cells. The meaningful messages …

Cancer promotion, development, and malignant transformation is greatly influenced by cell-
to-cell interactions in a complex tissue microenvironment. Cancer and stromal cells secrete …

Prostate cancer (PCa) is the most common solid tumor in men. While patients with local PCa
have better prognostic survival, patients with metastatic PCa have relatively high mortality …

Anthracycline/taxane-based chemotherapy regimens are usually used as neoadjuvant
chemotherapies to decrease tumour size and prevent metastasis of advanced breast cancer …

The cancer microenvironment plays a central role in cancer development, growth, and
homeostasis. This paradigm suggests that cancer fibroblasts support cancers, probably in …

Complexity in mechanisms that drive cancer development and progression is exemplified by
the transforming growth factor β (TGF-β) signaling pathway, which suppresses early-stage …

The highlights of cancer research include the discovery of exosomes, which are small (30-
100 nm) sized vesicular nanoparticles released virtually by all cells. Tumor-derived …

Abstract Background Immune‐checkpoint inhibitors (ICIs) are an effective therapeutic
strategy, improving the survival of patients with lung cancer compared with conventional …

Introduction: Tumor-derived exosomes (TEX) and their role in tumor progression by
accelerating angiogenesis are of great current interest. A better understanding of the …

Abstract Cancer-associated fibroblasts (CAFs), one of the major components of a tumour
microenvironment, comprise heterogeneous populations involved in tumour progression …