Hypertrabeculation and noncompaction are congenital or acquired abnormalities of
myocardial anatomy characterized by prominent trabeculations, intertrabecular recesses …

Mitochondrial diseases (MD) include an heterogenous group of systemic disorders caused
by sporadic or inherited mutations in nuclear (nDNA) or mitochondrial DNA (mtDNA) …

Life-threatening neuromuscular disorders affect a small, but growing group of patients in the
intensive care unit who present special management problems, as well as great therapeutic …

Cardiac disease is a common clinical manifestation present in a variety of neuromuscular
disorders, most notably the muscular dystrophies. Heart disease may produce the …

Introduction: LMNA-related muscular dystrophy is a rare entity that produce “laminopathies”
such as Emery–Dreifuss muscular dystrophy (EDMD), limb–girdle muscular dystrophy type …

Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels encode neuronal and
cardiac pacemaker currents. The composition of pacemaker channel complexes in different …

Background Progressive cardiomyopathy accounts for almost all mortality among Duchenne
muscular dystrophy (DMD) patients. ‍ Thus, our aim was to comprehensively characterize …

Inherited muscular diseases (MDs) are genetic degenerative disorders typically caused by
mutations in a single gene that affect striated muscle and result in progressive weakness …

Cardiac involvement is common and may be the presenting or predominant manifestation in
a variety of neuromuscular disorders, most notably the inherited muscle disorders, or …

Since the sentinel description of exercise-triggered ventricular arrhythmias in 21 children,
our recognition and understanding of catecholaminergic polymorphic ventricular tachycardia …