Animal models suggest that stress-induced hormonal changes in the mother during
pregnancy lead to enduring changes in the fetus and empirical links between prenatal …

BACKGROUND: Hypothalamus–Pituitary–Adrenal (HPA) axis dysregulation is often seen in
major depression, and is thought to represent a trait vulnerability–rather than merely an …

A substantial body of research on the pathophysiology of negative health outcomes has
focused on dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis. Maladaptive …

BACKGROUND: Although many demographic and clinical characteristics have been
suggested to predict treatment outcome of depression, they provide only a weak prediction …

Context: A substantial body of research on the pathophysiology of chronic fatigue syndrome
(CFS) has focused on hypothalamic-pituitary-adrenal axis dysregulation. The cortisol …

Hair cortisol concentrations (HCC) are receiving increased attention as a novel biomarker of
psychophysiological responses to chronic stress, with potential relevance for …

Impairments in either “cool” or “hot” processes may represent two pathways to deficient
decision-making. Whereas cool processes are associated with cognitive and rational …

Objective: This 4-year longitudinal study examined the different roles of perceived stress in
the association between older adults' physical activities and physical health. We …

Stress and negative affective states are associated with cortisol in everyday life. However, it
remains unclear what types of stressors and which affective states yield these associations …

The distinction between pseudo-Cushing's states (PCS) and Cushing's syndrome (CS)
poses a significant clinical challenge even for expert endocrinologists. A patient's clinical …