Nerolidol (Ner), a major component of many plant essential oils, is known for its various
biological properties. However, the low solubility of Ner in water and its susceptibility to …

Albendazole (ABZ) exhibits a potent antiparasitic activity against a broad spectrum of
parasites. Unfortunately, the very low water solubility of ABZ (0.2 μg mL− 1, 0.7 μM) impairs …

Effective and safe ophthalmic anesthesia is essential for the delivery of ophthalmic
perioperative care both for children and adults. Recent years have seen a major change in …

We investigated the ionization profiles for open-ring (OR) and closed-ring (CR) forms of
midazolam and drug-binding modes with heptakis-(2, 3, 6-tri-O-methyl)-β-cyclodextrin …

Moringin, obtained via enzymatic conversion of the glucosinolate precursor glucomoringin,
is an uncommon member of the isothiocyanate class, and has been proven to possess a …

Rifampicin (Rif) is a broad spectrum antibiotic used as a first line agent in the treatment of
mycobacterial infections. However, its low solubility and reduced stability in water limit its …

trans-Resveratrol (RSV) is a natural phenolic molecule of the stilbene family known for its
anti-oxidant properties in the field of nutraceuticals and cosmetics. Its production by …

Purpose The objective of this study was to assess the bioavailability and the sedative effect
of a single-dose administration of an innovative oral solution of midazolam containing γ …

Clotrimazole (CTZ) and cyclodextrin (CD) inclusion complexes having improved apparent
water solubility were obtained from phase solubility diagrams. β‐CD (1.5% w/w) and …

Ozalin®, a novel oral solution of 0.2% midazolam, is an effective option for moderate
sedation prior to a therapeutic or diagnostic procedure, and as premedication before …