Ageing is a major risk factor for developing many neurodegenerative diseases. Cellular
senescence is a homeostatic biological process that has a key role in driving ageing. There …

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …

Early intervention with high-efficacy disease-modifying therapy (HE DMT) may be the best
strategy to delay irreversible neurological damage and progression of multiple sclerosis …

Because the treatment of multiple sclerosis (MS) may span decades, the need often arises to
make changes to the treatment plan in order to accommodate changing circumstances …

Background SARS-CoV-2 viral infection causes COVID-19 that can result in severe acute
respiratory distress syndrome (ARDS), which can cause significant mortality, leading to …

Dimethyl fumarate (Tecfidera®) is approved for the treatment of relapsing forms of multiple
sclerosis (MS). Based on evidence from the clinical trial and real-world settings, dimethyl …

The multiple sclerosis (MS) neurotherapeutic landscape is rapidly evolving. New disease-
modifying therapies (DMTs) with improved efficacy and safety, in addition to an expanding …

Background and Objectives Several studies have assessed risk factors associated with the
severity of COVID-19 outcomes in people with multiple sclerosis (PwMS). The potential role …

Multiple sclerosis (MS) is the most common chronic autoimmune neurological disease. Its
therapeutic management has drastically evolved in the recent years with the development of …

In this independent, multicenter, post-marketing study, we directly compare induction
immunosuppression versus escalation strategies on the risk of reaching the disability …