The high prevalence of obesity is associated with an enormous medical, social, and
economic burden. The metabolic dysfunction, dyslipidaemia, and inflammation caused by …

Over the past decades, the human life span has dramatically increased, and therefore, a
steady increase in diseases associated with age (such as Alzheimer's disease and …

Accumulating studies suggest that overnutrition-associated obesity may lead to
development of type 2 diabetes mellitus and metabolic syndromes (MetS). MetS and its …

Abstract High-fat diet (HFD)-induced obesity is a risk factor for cognitive impairment in
Alzheimer's disease (AD). It has been reported that two typical neuropathological markers of …

The worldwide epidemic of obesity has become an important public health issue, with
serious psychological and social consequences. Obesity is a multifactorial disorder in which …

Excessive consumption of diets high in saturated fat and sugar impairs short-term spatial
recognition memory in both humans and rodents. Several studies have identified …

Although the high prevalence of anxiety in obesity increasingly emerges as significant risk
factor for related severe health complications, the underlying pathophysiological …

Background Diabetic individuals have increased circulating inflammatory mediators which
are implicated as underlying causes of neuroinflammation and memory deficits. Tonicity …

An intermittent fasting (IF) regimen has been shown to protect against metabolic dysfunction-
associated steatohepatitis (MASH). However, the precise mechanism remains unclear …

Obesity causes brain injuries with inflammatory and structural changes, leading to
neurodegeneration. Although increased circulating lipocalin 2 (LCN2) level has been …