[HTML][HTML] Antifungal therapy: new advances in the understanding and treatment of mycosis

L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

[HTML][HTML] Fungal biofilms and polymicrobial diseases

CB Costa-Orlandi, JCO Sardi, NS Pitangui… - Journal of Fungi, 2017 - mdpi.com
Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and
filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized …

A holistic review on Cryptococcus neoformans

SS Rathore, J Sathiyamoorthy, C Lalitha… - Microbial …, 2022 - Elsevier
Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

From moths to caterpillars: Ideal conditions for Galleria mellonella rearing for in vivo microbiological studies

AL Jorjão, LD Oliveira, L Scorzoni… - Virulence, 2018 - Taylor & Francis
Galleria mellonella is a well-accepted insect model for the study of pathogen-host
interactions and antimicrobial compounds. The main advantages of this model include the …

[HTML][HTML] Rearing and Maintenance of Galleria mellonella and Its Application to Study Fungal Virulence

C Firacative, A Khan, S Duan, K Ferreira-Paim… - Journal of Fungi, 2020 - mdpi.com
Galleria mellonella larvae have been widely used as alternative non-mammalian models for
the study of fungal virulence and pathogenesis. The larvae can be acquired in small …

Fungal immunity and pathogenesis in mammals versus the invertebrate model organism Galleria mellonella

D FQ Smith, A Casadevall - Pathogens and disease, 2021 - academic.oup.com
In recent decades, Galleria mellonella (Lepidoptera: Pyralidae) have emerged as a model
system to explore experimental aspects of fungal pathogenesis. The benefits of the G …

[HTML][HTML] The anti-helminthic compound mebendazole has multiple antifungal effects against Cryptococcus neoformans

LS Joffe, R Schneider, W Lopes, R Azevedo… - Frontiers in …, 2017 - frontiersin.org
Cryptococcus neoformans is the most lethal pathogen of the central nervous system. The
gold standard treatment of cryptococcosis, a combination of amphotericin B with 5 …

Biofilm, adherence, and hydrophobicity as virulence factors in Malassezia furfur

L Angiolella, C Leone, F Rojas, J Mussin… - Medical …, 2018 - academic.oup.com
Malassezia species are natural inhabitants of the healthy skin. However, under certain
conditions, they may cause or exacerbate several skin diseases. The ability of this fungus to …

Delineating the Biofilm Inhibition Mechanisms of Phenolic and Aldehydic Terpenes against Cryptococcus neoformans

P Kumari, N Arora, A Chatrath, R Gangwar, V Pruthi… - ACS …, 2019 - ACS Publications
The recalcitrant biofilm formed by fungus Cryptococcus neoformans is a life-threatening
pathogenic condition responsible for further intensifying cryptococcosis. Considering the …

[HTML][HTML] Stenotrophomonas maltophilia phenotypic and genotypic diversity during a 10-year colonization in the lungs of a cystic fibrosis patient

A Pompilio, V Crocetta, D Ghosh… - Frontiers in …, 2016 - frontiersin.org
The present study was carried out to understand the adaptive strategies developed by
Stenotrophomonas maltophilia for chronic colonization of the cystic fibrosis (CF) lung. For …