HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …

Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these
species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To …

Environmental pathogens move from ecological niches to mammalian hosts, requiring
adaptation to dramatically different environments. Microbes that disseminate farther …

Cryptococcus neoformans is a significant fungal pathogen of immunocompromised patients.
Many questions remain regarding the function of macrophages in normal clearance of …

Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with
macrophages is a key event determining the outcome of infection. Urease is a major …

The pathogenic fungus Cryptococcus neoformans exhibits morphological changes in cell
size during lung infection, producing both typical size 5 to 7 μm cells and large titan cells (> …

In immunocompromised individuals, Aspergillus fumigatus causes invasive fungal disease
that is often difficult to treat. Exactly how immune mechanisms control A. fumigatus in …

Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …